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trpD anthranilate synthase, component II [ Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 ]

Gene ID: 1253243, updated on 10-Oct-2024

Summary

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Gene symbol
trpD
Gene description
anthranilate synthase, component II
Locus tag
STM1724
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 (strain: LT2, serovar: Typhimurium, sub-species: enterica, culture-collection: ATCC:700720, culture-collection: SGSC:1412, type-material: type strain of Salmonella enterica)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Salmonella
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Genomic context

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Sequence:
NC_003197.2 (1820092..1821701)

NC_003197.2Genomic Context describing neighboring genes Neighboring gene putative translation factor Neighboring gene trpR controlled transcriptional unit in the 5' upstream region of the trp operon Neighboring gene trp operon leader peptide Neighboring gene anthranilate synthase, component I Neighboring gene N-(5-phosphoribosyl)anthranilate isomerase Neighboring gene tryptophan synthase, beta protein Neighboring gene tryptophan synthase, alpha protein Neighboring gene putative cytoplasmic protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003197.2

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. PurF-independent phosphoribosyl amine formation in yjgF mutants of Salmonella enterica utilizes the tryptophan biosynthetic enzyme complex anthranilate synthase-phosphoribosyltransferase. Browne BA, et al. J Bacteriol, 2006 Oct. PMID 16980480, Free PMC Article
  2. Complete genome sequence of Salmonella enterica serovar Typhimurium LT2. McClelland M, et al. Nature, 2001 Oct 25. PMID 11677609

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The tryptophan biosynthetic enzyme complex anthranilate synthase-phosphoribosyltransferase, composed of the TrpD and TrpE proteins, was shown to be essential for phosphoribosyl amine formation in strains lacking both yjgF and purF.
    Title: PurF-independent phosphoribosyl amine formation in yjgF mutants of Salmonella enterica utilizes the tryptophan biosynthetic enzyme complex anthranilate synthase-phosphoribosyltransferase.
Submit: New GeneRIF Correction

General gene information

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regulatory

  • Loc: 1820092-1820097 regulatory_class = ribosome_binding_site
  • Loc: 1821643-1821651 regulatory_class = minus_35_signal
  • Loc: 1821669-1821677 regulatory_class = minus_10_signal
  • Loc: 1821694-1821699 regulatory_class = ribosome_binding_site

General protein information

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Preferred Names
anthranilate synthase, component II
NP_460683.1
  • bifunctional: glutamine amidotransferase and phosphoribosylanthranilate transferase; anthranilate synthase component II ]. (SW:TRPG_SALTY)

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003197.2 Reference assembly

    Range
    1820092..1821701
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    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_460683.1 anthranilate synthase, component II [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]

    See identical proteins and their annotated locations for NP_460683.1

    Status: PROVISIONAL

    UniProtKB/TrEMBL
    A0A5H8JFQ3, A0A5H8RCN5, A0A5T8RL19, A0A5U1ATS1, A0A5U7UV24, A0A612L2P3, A0A626FT53, A0A729WH81, A0A749J603, A0A757UGC6, A0A758VD94, A0A761I0F9, A0A762P8Z8, A0A762R1P7
    Conserved Domains (1) summary
    PRK09522
    Location:1 → 531
    PRK09522; bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P00905.4

Gene LinkOut

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Other Literature Sources
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Research Materials