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erbb2 erb-b2 receptor tyrosine kinase 2 [ Megalobrama amblycephala (Wuchang bream) ]

Gene ID: 125255361, updated on 11-Apr-2024

Summary

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Gene symbol
erbb2
Gene description
erb-b2 receptor tyrosine kinase 2
See related
EnsemblRapid:ENSMAYG00005013736
Gene type
protein coding
RefSeq status
MODEL
Organism
Megalobrama amblycephala
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Xenocyprididae; Xenocypridinae; Megalobrama
Orthologs
human zebrafish all
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Genomic context

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See erbb2 in Genome Data Viewer
Location:
chromosome: LG20
Exon count:
27
Annotation release Status Assembly LG Location
100 current ASM1881202v1 (GCF_018812025.1) LG20 NC_063063.1 (8346261..8389289, complement)

Linkage Group LG20 - NC_063063.1Genomic Context describing neighboring genes Neighboring gene translational activator of cytochrome c oxidase 1 Neighboring gene potassium voltage-gated channel, subfamily H (eag-related), member 6b Neighboring gene uncharacterized LOC125255350 Neighboring gene uncharacterized LOC125255980 Neighboring gene post-GPI attachment to proteins phospholipase 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_063063.1 Chromosome LG20 Reference ASM1881202v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neuron differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basal plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Megalobrama amblycephala Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1881202v1 Primary Assembly

Genomic

  1. NC_063063.1 Reference ASM1881202v1 Primary Assembly

    Range
    8346261..8389289 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_048170537.1 → XP_048026494.1  LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-2

    Related
    ENSMAYP00005032900.1, ENSMAYT00005035943.1
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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