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CRKL CRK like proto-oncogene, adaptor protein [ Ursus americanus (American black bear) ]

Gene ID: 123795650, updated on 22-Mar-2024

Summary

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Gene symbol
CRKL
Gene description
CRK like proto-oncogene, adaptor protein
Gene type
protein coding
RefSeq status
MODEL
Organism
Ursus americanus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus
Orthologs
human mouse all
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Genomic context

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See CRKL in Genome Data Viewer
Location:
chromosome: Un
Exon count:
3
Annotation release Status Assembly Chr Location
100 current gsc_jax_bbear_1.0 (GCF_020975775.1) Unplaced Scaffold NW_025577628.1 (1973774..2010884)

NW_025577628.1Genomic Context describing neighboring genes Neighboring gene phosphatidylinositol 4-kinase alpha Neighboring gene serpin family D member 1 Neighboring gene synaptosome associated protein 29 Neighboring gene uncharacterized LOC123795649 Neighboring gene uncharacterized LOC123795656 Neighboring gene apoptosis inducing factor mitochondria associated 3 Neighboring gene leucine zipper like post translational regulator 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_025577628 Unplaced Scaffold Reference gsc_jax_bbear_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of ERK1 and ERK2 cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
crk-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ursus americanus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference gsc_jax_bbear_1.0 Primary Assembly

Genomic

  1. NW_025577628.1 Reference gsc_jax_bbear_1.0 Primary Assembly

    Range
    1973774..2010884
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_045802544.1 → XP_045658500.1  crk-like protein

    UniProtKB/TrEMBL
    A0A452QS13
    Conserved Domains (3) summary
    cd09926
    Location:6 → 106
    SH2_CRK_like; Src homology 2 domain found in cancer-related signaling adaptor protein CRK
    cd11758
    Location:126 → 180
    SH3_CRK_N; N-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins
    cd11759
    Location:237 → 293
    SH3_CRK_C; C-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins
Nucleotide Protein
Heading Accession and Version

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