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PLCG1 phospholipase C gamma 1 [ Gracilinanus agilis (Agile Gracile Mouse Opossum) ]

Gene ID: 123237416, updated on 22-Mar-2024

Summary

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Gene symbol
PLCG1
Gene description
phospholipase C gamma 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Gracilinanus agilis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Metatheria; Didelphimorphia; Didelphidae; Gracilinanus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
32
Annotation release Status Assembly Chr Location
100 current AgileGrace (GCF_016433145.1) 2 NC_058131.1 (342614910..342688792)

Chromosome 2 - NC_058131.1Genomic Context describing neighboring genes Neighboring gene DEAH-box helicase 35 Neighboring gene DNA topoisomerase I Neighboring gene zinc fingers and homeoboxes 3 Neighboring gene lipin 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_058131.1 Chromosome 2 Reference AgileGrace Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol phospholipase C activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phospholipid catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of epithelial cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gracilinanus agilis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference AgileGrace Primary Assembly

Genomic

  1. NC_058131.1 Reference AgileGrace Primary Assembly

    Range
    342614910..342688792
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_044664322.1 → XP_044520257.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1

    Conserved Domains (10) summary
    smart00149
    Location:955 → 1070
    PLCYc; Phospholipase C, catalytic domain (part); domain Y
    cd00275
    Location:1088 → 1212
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08592
    Location:320 → 467
    PI-PLCc_gamma; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-gamma
    cd09932
    Location:664 → 766
    SH2_C-SH2_PLC_gamma_like; C-terminal Src homology 2 (C-SH2) domain in Phospholipase C gamma
    cd10341
    Location:546 → 650
    SH2_N-SH2_PLC_gamma_like; N-terminal Src homology 2 (N-SH2) domain in Phospholipase C gamma
    cd11970
    Location:792 → 850
    SH3_PLCgamma1; Src homology 3 domain of Phospholipase C (PLC) gamma 1
    cd13234
    Location:865 → 934
    PHsplit_PLC_gamma; Phospholipase C-gamma Split pleckstrin homology (PH) domain
    cd13362
    Location:30 → 152
    PH_PLC_gamma; Phospholipase C-gamma (PLC-gamma) pleckstrin homology (PH) domain
    cd16214
    Location:157 → 307
    EFh_PI-PLCgamma1; EF-hand motif found in phosphoinositide phospholipase C gamma 1 (PI-PLC-gamma1)
    cl17171
    Location:490 → 524
    PH-like; Pleckstrin homology-like domain

  2. XM_044664323.1 → XP_044520258.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X2

    Conserved Domains (10) summary
    smart00149
    Location:954 → 1069
    PLCYc; Phospholipase C, catalytic domain (part); domain Y
    cd00275
    Location:1087 → 1211
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08592
    Location:319 → 466
    PI-PLCc_gamma; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-gamma
    cd09932
    Location:663 → 765
    SH2_C-SH2_PLC_gamma_like; C-terminal Src homology 2 (C-SH2) domain in Phospholipase C gamma
    cd10341
    Location:545 → 649
    SH2_N-SH2_PLC_gamma_like; N-terminal Src homology 2 (N-SH2) domain in Phospholipase C gamma
    cd11970
    Location:791 → 849
    SH3_PLCgamma1; Src homology 3 domain of Phospholipase C (PLC) gamma 1
    cd13234
    Location:864 → 933
    PHsplit_PLC_gamma; Phospholipase C-gamma Split pleckstrin homology (PH) domain
    cd13362
    Location:29 → 151
    PH_PLC_gamma; Phospholipase C-gamma (PLC-gamma) pleckstrin homology (PH) domain
    cd16214
    Location:156 → 306
    EFh_PI-PLCgamma1; EF-hand motif found in phosphoinositide phospholipase C gamma 1 (PI-PLC-gamma1)
    cl17171
    Location:489 → 523
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
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