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CISH cytokine inducible SH2 containing protein [ Varanus komodoensis (Komodo dragon) ]

Gene ID: 123034198, updated on 22-Mar-2024

Summary

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Gene symbol
CISH
Gene description
cytokine inducible SH2 containing protein
Locus tag
EYD10_04328
See related
Ensembl:ENSVKKG00000015007
Gene type
protein coding
RefSeq status
MODEL
Organism
Varanus komodoensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Anguimorpha; Paleoanguimorpha; Varanoidea; Varanidae; Varanus
Orthologs
human mouse all
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Genomic context

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See CISH in Genome Data Viewer
Location:
chromosome: Un
Exon count:
3
Annotation release Status Assembly Chr Location
100 current ASM479886v1 (GCF_004798865.1) Unplaced Scaffold NW_025336346.1 (4145476..4154410, complement)

NW_025336346.1Genomic Context describing neighboring genes Neighboring gene chromosome unknown C3orf18 homolog Neighboring gene HemK methyltransferase family member 1 Neighboring gene MAPK activated protein kinase 3 Neighboring gene dedicator of cytokinesis 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_025336346 Unplaced Scaffold Reference ASM479886v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cytokine-inducible SH2-containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Varanus komodoensis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM479886v1

Genomic

  1. NW_025336346.1 Reference ASM479886v1

    Range
    4145476..4154410 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_044451402.1 → XP_044307337.1  cytokine-inducible SH2-containing protein

    UniProtKB/TrEMBL
    A0A8D2LJZ6
    Related
    ENSVKKP00000022555.1, ENSVKKT00000023114.1
    Conserved Domains (2) summary
    cd10718
    Location:88 → 175
    SH2_CIS; Src homology 2 (SH2) domain found in cytokine-inducible SH2-containing protein (CIS)
    cl02533
    Location:218 → 258
    SOCS; SOCS (suppressors of cytokine signaling) box. The SOCS box is found in the C-terminal region of CIS/SOCS family proteins (in combination with a SH2 domain), ASBs (ankyrin repeat-containing proteins with a SOCS box), SSBs (SPRY domain-containing proteins ...
Nucleotide Protein
Heading Accession and Version

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