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SFRP1 secreted frizzled related protein 1 [ Varanus komodoensis (Komodo dragon) ]

Gene ID: 123027025, updated on 22-Mar-2024

Summary

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Gene symbol
SFRP1
Gene description
secreted frizzled related protein 1
See related
Ensembl:ENSVKKG00000015451
Gene type
protein coding
RefSeq status
MODEL
Organism
Varanus komodoensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Anguimorpha; Paleoanguimorpha; Varanoidea; Varanidae; Varanus
Orthologs
human mouse all
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Genomic context

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See SFRP1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
3
Annotation release Status Assembly Chr Location
100 current ASM479886v1 (GCF_004798865.1) Unplaced Scaffold NW_025335762.1 (1204386..1241160)

NW_025335762.1Genomic Context describing neighboring genes Neighboring gene GINS complex subunit 4 Neighboring gene golgin A7 Neighboring gene zinc finger matrin-type 4 Neighboring gene uncharacterized LOC123027182

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_025335762 Unplaced Scaffold Reference ASM479886v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Wnt-protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in non-canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
secreted frizzled-related protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Varanus komodoensis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM479886v1

Genomic

  1. NW_025335762.1 Reference ASM479886v1

    Range
    1204386..1241160
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_044437368.1 → XP_044293303.1  secreted frizzled-related protein 1

    UniProtKB/TrEMBL
    A0A8D2LK55, A0A8D2LLS6
    Related
    ENSVKKP00000023312.1, ENSVKKT00000023892.1
    Conserved Domains (2) summary
    cd07443
    Location:52 → 175
    CRD_SFRP1; Cysteine-rich domain of the secreted frizzled-related protein 1 (SFRP1), a regulator of Wnt activity
    cl02512
    Location:184 → 290
    NTR_like; NTR_like domain; a beta barrel with an oligosaccharide/oligonucleotide-binding fold found in netrins, complement proteins, tissue inhibitors of metalloproteases (TIMP), and procollagen C-proteinase enhancers (PCOLCE), amongst others. In netrins, the ...
Nucleotide Protein
Heading Accession and Version

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