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TRAF2 TNF receptor associated factor 2 [ Neogale vison (American mink) ]

Gene ID: 122917083, updated on 22-Mar-2024

Summary

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Gene symbol
TRAF2
Gene description
TNF receptor associated factor 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Neogale vison
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae; Mustelinae; Neogale
Also known as
B1AMX9
Orthologs
human mouse all
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Genomic context

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See TRAF2 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
12
Annotation release Status Assembly Chr Location
100 current ASM_NN_V1 (GCF_020171115.1) 9 NC_058099.1 (988478..1011238, complement)

Chromosome 9 - NC_058099.1Genomic Context describing neighboring genes Neighboring gene complement C8 gamma chain Neighboring gene F-box and WD repeat domain containing 5 Neighboring gene collagen alpha-1(I) chain-like Neighboring gene endothelial differentiation related factor 1 Neighboring gene MAM domain containing 4

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_058099.1 Chromosome 9 Reference ASM_NN_V1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables tumor necrosis factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin-protein transferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in activation of NF-kappaB-inducing kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of JNK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of NF-kappaB transcription factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein K63-linked ubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein autoubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tumor necrosis factor-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasmic side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of plasma membrane signaling receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
TNF receptor-associated factor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Neovison vison Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM_NN_V1 Primary Assembly

Genomic

  1. NC_058099.1 Reference ASM_NN_V1 Primary Assembly

    Range
    988478..1011238 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_044264485.1 → XP_044120420.1  TNF receptor-associated factor 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C7BCK4
    Conserved Domains (3) summary
    cd03778
    Location:351 → 514
    MATH_TRAF2; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF2 subfamily, TRAF domain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of transcription factors and the ...
    pfam02176
    Location:178 → 235
    zf-TRAF; TRAF-type zinc finger
    cd16639
    Location:32 → 73
    RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins

  2. XM_044264483.1 → XP_044120418.1  TNF receptor-associated factor 2 isoform X3

    Conserved Domains (3) summary
    cd03778
    Location:318 → 481
    MATH_TRAF2; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF2 subfamily, TRAF domain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of transcription factors and the ...
    pfam02176
    Location:145 → 202
    zf-TRAF; TRAF-type zinc finger
    cd16639
    Location:32 → 73
    RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins

  3. XM_044264484.1 → XP_044120419.1  TNF receptor-associated factor 2 isoform X4

    UniProtKB/TrEMBL
    A0A8C7AZX1
    Conserved Domains (3) summary
    cd03778
    Location:297 → 460
    MATH_TRAF2; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF2 subfamily, TRAF domain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of transcription factors and the ...
    pfam02176
    Location:124 → 181
    zf-TRAF; TRAF-type zinc finger
    cd16639
    Location:32 → 73
    RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins

  4. XM_044264482.1 → XP_044120417.1  TNF receptor-associated factor 2 isoform X2

    Conserved Domains (3) summary
    cd03778
    Location:349 → 512
    MATH_TRAF2; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF2 subfamily, TRAF domain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of transcription factors and the ...
    pfam02176
    Location:178 → 235
    zf-TRAF; TRAF-type zinc finger
    cd16639
    Location:32 → 73
    RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins

  5. XM_044264481.1 → XP_044120416.1  TNF receptor-associated factor 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C7BCK4
    Conserved Domains (3) summary
    cd03778
    Location:351 → 514
    MATH_TRAF2; Tumor Necrosis Factor Receptor (TNFR) Associated Factor (TRAF) family, TRAF2 subfamily, TRAF domain; TRAF molecules serve as adapter proteins that link TNFRs and downstream kinase cascades resulting in the activation of transcription factors and the ...
    pfam02176
    Location:178 → 235
    zf-TRAF; TRAF-type zinc finger
    cd16639
    Location:32 → 73
    RING-HC_TRAF2; RING finger, HC subclass, found in tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and similar proteins
Nucleotide Protein
Heading Accession and Version

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