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EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 [ Neogale vison (American mink) ]

Gene ID: 122915170, updated on 22-Mar-2024

Summary

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Gene symbol
EIF2AK2
Gene description
eukaryotic translation initiation factor 2 alpha kinase 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Neogale vison
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae; Mustelinae; Neogale
Also known as
E2AK2
Orthologs
human mouse all
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Genomic context

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See EIF2AK2 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
19
Annotation release Status Assembly Chr Location
100 current ASM_NN_V1 (GCF_020171115.1) 8 NC_058098.1 (118255946..118286354, complement)

Chromosome 8 - NC_058098.1Genomic Context describing neighboring genes Neighboring gene HEAT repeat containing 5B Neighboring gene G-patch domain containing 11 Neighboring gene transfer RNA lysine (anticodon CUU) Neighboring gene fibronectin type III domain-containing protein 4-like Neighboring gene intraflagellar transport protein 172 homolog Neighboring gene uncharacterized LOC122915477

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_058098.1 Chromosome 8 Reference ASM_NN_V1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables double-stranded RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
interferon-induced, double-stranded RNA-activated protein kinase
Names
Interferon-induced, double-stranded RNA-activated protein kinase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Neovison vison Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM_NN_V1 Primary Assembly

Genomic

  1. NC_058098.1 Reference ASM_NN_V1 Primary Assembly

    Range
    118255946..118286354 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_044261793.1 → XP_044117728.1  interferon-induced, double-stranded RNA-activated protein kinase isoform X3

    UniProtKB/TrEMBL
    A0A8C7BUS3
    Conserved Domains (3) summary
    cd19904
    Location:102 → 168
    DSRM_EIF2AK2_rpt2; second double-stranded RNA binding motif of eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2) and similar proteins
    cl00054
    Location:9 → 62
    DSRM_SF; double-stranded RNA binding motif (DSRM) superfamily
    cl21453
    Location:256 → 487
    PKc_like; Protein Kinases, catalytic domain

  2. XM_044261792.1 → XP_044117727.1  interferon-induced, double-stranded RNA-activated protein kinase isoform X2

    UniProtKB/TrEMBL
    A0A8C7BQ00
    Conserved Domains (3) summary
    cd19904
    Location:102 → 168
    DSRM_EIF2AK2_rpt2; second double-stranded RNA binding motif of eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2) and similar proteins
    cl00054
    Location:9 → 62
    DSRM_SF; double-stranded RNA binding motif (DSRM) superfamily
    cl21453
    Location:266 → 523
    PKc_like; Protein Kinases, catalytic domain

  3. XM_044261786.1 → XP_044117721.1  interferon-induced, double-stranded RNA-activated protein kinase isoform X1

    UniProtKB/TrEMBL
    A0A8C7BQ00, U6CT75
    Conserved Domains (3) summary
    cd19904
    Location:102 → 168
    DSRM_EIF2AK2_rpt2; second double-stranded RNA binding motif of eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2) and similar proteins
    cl00054
    Location:9 → 62
    DSRM_SF; double-stranded RNA binding motif (DSRM) superfamily
    cl21453
    Location:266 → 528
    PKc_like; Protein Kinases, catalytic domain

  4. XM_044261787.1 → XP_044117722.1  interferon-induced, double-stranded RNA-activated protein kinase isoform X1

    UniProtKB/TrEMBL
    A0A8C7BQ00, U6CT75
    Conserved Domains (3) summary
    cd19904
    Location:102 → 168
    DSRM_EIF2AK2_rpt2; second double-stranded RNA binding motif of eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2) and similar proteins
    cl00054
    Location:9 → 62
    DSRM_SF; double-stranded RNA binding motif (DSRM) superfamily
    cl21453
    Location:266 → 528
    PKc_like; Protein Kinases, catalytic domain

  5. XM_044261789.1 → XP_044117724.1  interferon-induced, double-stranded RNA-activated protein kinase isoform X1

    UniProtKB/TrEMBL
    A0A8C7BQ00, U6CT75
    Conserved Domains (3) summary
    cd19904
    Location:102 → 168
    DSRM_EIF2AK2_rpt2; second double-stranded RNA binding motif of eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2) and similar proteins
    cl00054
    Location:9 → 62
    DSRM_SF; double-stranded RNA binding motif (DSRM) superfamily
    cl21453
    Location:266 → 528
    PKc_like; Protein Kinases, catalytic domain

  6. XM_044261791.1 → XP_044117726.1  interferon-induced, double-stranded RNA-activated protein kinase isoform X1

    UniProtKB/TrEMBL
    A0A8C7BQ00, U6CT75
    Conserved Domains (3) summary
    cd19904
    Location:102 → 168
    DSRM_EIF2AK2_rpt2; second double-stranded RNA binding motif of eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2) and similar proteins
    cl00054
    Location:9 → 62
    DSRM_SF; double-stranded RNA binding motif (DSRM) superfamily
    cl21453
    Location:266 → 528
    PKc_like; Protein Kinases, catalytic domain

  7. XM_044261788.1 → XP_044117723.1  interferon-induced, double-stranded RNA-activated protein kinase isoform X1

    UniProtKB/TrEMBL
    A0A8C7BQ00, U6CT75
    Conserved Domains (3) summary
    cd19904
    Location:102 → 168
    DSRM_EIF2AK2_rpt2; second double-stranded RNA binding motif of eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2) and similar proteins
    cl00054
    Location:9 → 62
    DSRM_SF; double-stranded RNA binding motif (DSRM) superfamily
    cl21453
    Location:266 → 528
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
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