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GRN granulin precursor [ Neogale vison (American mink) ]

Gene ID: 122906140, updated on 22-Mar-2024

Summary

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Gene symbol
GRN
Gene description
granulin precursor
Gene type
protein coding
RefSeq status
MODEL
Organism
Neogale vison
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae; Mustelinae; Neogale
Orthologs
human mouse all
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Genomic context

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See GRN in Genome Data Viewer
Location:
chromosome: 5
Exon count:
13
Annotation release Status Assembly Chr Location
100 current ASM_NN_V1 (GCF_020171115.1) 5 NC_058095.1 (18563556..18570245, complement)

Chromosome 5 - NC_058095.1Genomic Context describing neighboring genes Neighboring gene integrin subunit alpha 2b Neighboring gene family with sequence similarity 171 member A2 Neighboring gene 5S ribosomal RNA Neighboring gene solute carrier family 25 member 39

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_058095.1 Chromosome 5 Reference ASM_NN_V1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Spatiotemporal expression pattern of progranulin in embryo implantation and placenta formation suggests a role in cell proliferation, remodeling, and angiogenesis. Desmarais JA, et al. Reproduction, 2008 Aug. PMID 18469036
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
progranulin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Neovison vison Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM_NN_V1 Primary Assembly

Genomic

  1. NC_058095.1 Reference ASM_NN_V1 Primary Assembly

    Range
    18563556..18570245 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_044247776.1 → XP_044103711.1  progranulin

    UniProtKB/TrEMBL
    A0A8C7CB44, A0A8C7EWW8
    Conserved Domains (2) summary
    smart00277
    Location:279 → 329
    GRAN; Granulin
    cl02546
    Location:66 → 112
    Granulin
Nucleotide Protein
Heading Accession and Version

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