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CRKL CRK like proto-oncogene, adaptor protein [ Neogale vison (American mink) ]

Gene ID: 122903191, updated on 22-Mar-2024

Summary

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Gene symbol
CRKL
Gene description
CRK like proto-oncogene, adaptor protein
Gene type
protein coding
RefSeq status
MODEL
Organism
Neogale vison
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae; Mustelinae; Neogale
Orthologs
human mouse all
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Genomic context

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See CRKL in Genome Data Viewer
Location:
chromosome: 3
Exon count:
3
Annotation release Status Assembly Chr Location
100 current ASM_NN_V1 (GCF_020171115.1) 3 NC_058093.1 (213020819..213060384, complement)

Chromosome 3 - NC_058093.1Genomic Context describing neighboring genes Neighboring gene leucine zipper like post translational regulator 1 Neighboring gene apoptosis inducing factor mitochondria associated 3 Neighboring gene synaptosome associated protein 29 Neighboring gene phosphatidylinositol 4-kinase alpha Neighboring gene serpin family D member 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_058093.1 Chromosome 3 Reference ASM_NN_V1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of ERK1 and ERK2 cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
crk-like protein
Names
Crk-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Neovison vison Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM_NN_V1 Primary Assembly

Genomic

  1. NC_058093.1 Reference ASM_NN_V1 Primary Assembly

    Range
    213020819..213060384 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_044243771.1 → XP_044099706.1  crk-like protein

    UniProtKB/TrEMBL
    A0A8C7BRQ1, U6CS22
    Conserved Domains (3) summary
    cd09926
    Location:6 → 106
    SH2_CRK_like; Src homology 2 domain found in cancer-related signaling adaptor protein CRK
    cd11758
    Location:126 → 180
    SH3_CRK_N; N-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins
    cd11759
    Location:237 → 293
    SH3_CRK_C; C-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins
Nucleotide Protein
Heading Accession and Version

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