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CAPN3 calpain 3 [ Neogale vison (American mink) ]

Gene ID: 122892893, updated on 22-Mar-2024

Summary

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Gene symbol
CAPN3
Gene description
calpain 3
Gene type
protein coding
RefSeq status
MODEL
Organism
Neogale vison
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Musteloidea; Mustelidae; Mustelinae; Neogale
Also known as
F8W8F5
Orthologs
human mouse all
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Genomic context

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See CAPN3 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
24
Annotation release Status Assembly Chr Location
100 current ASM_NN_V1 (GCF_020171115.1) 13 NC_058103.1 (85040048..85089586, complement)

Chromosome 13 - NC_058103.1Genomic Context describing neighboring genes Neighboring gene synaptosome associated protein 23 Neighboring gene KATNB1-like protein 1 Neighboring gene heterogeneous nuclear ribonucleoprotein A1-like Neighboring gene zinc finger protein 106 Neighboring gene glucosidase alpha, neutral C Neighboring gene U4 spliceosomal RNA Neighboring gene U6 spliceosomal RNA Neighboring gene transmembrane protein 87A

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_058103.1 Chromosome 13 Reference ASM_NN_V1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium-dependent cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
calpain-3
Names
Calpain 3, (p94)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Neovison vison Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM_NN_V1 Primary Assembly

Genomic

  1. NC_058103.1 Reference ASM_NN_V1 Primary Assembly

    Range
    85040048..85089586 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_044229533.1 → XP_044085468.1  calpain-3 isoform X3

    UniProtKB/TrEMBL
    A0A8C7BYP7, A0A8C7BYR0
    Conserved Domains (3) summary
    smart00230
    Location:61 → 377
    CysPc; Calpain-like thiol protease family
    cd00214
    Location:379 → 536
    Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...
    cd16190
    Location:561 → 729
    EFh_PEF_CAPN3; Calcium-activated neutral

  2. XM_044229531.1 → XP_044085466.1  calpain-3 isoform X1

    UniProtKB/TrEMBL
    A0A8C7BM53, A0A8C7BYP7
    Conserved Domains (3) summary
    smart00230
    Location:61 → 425
    CysPc; Calpain-like thiol protease family
    cd00214
    Location:427 → 584
    Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...
    cd16190
    Location:647 → 815
    EFh_PEF_CAPN3; Calcium-activated neutral

  3. XM_044229532.1 → XP_044085467.1  calpain-3 isoform X2

    UniProtKB/TrEMBL
    A0A8C7BRU6, A0A8C7BYP7
    Conserved Domains (3) summary
    smart00230
    Location:61 → 425
    CysPc; Calpain-like thiol protease family
    cd00214
    Location:427 → 584
    Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...
    cd16190
    Location:653 → 821
    EFh_PEF_CAPN3; Calcium-activated neutral
Nucleotide Protein
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