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ifih1 interferon induced with helicase C domain 1 [ Siniperca chuatsi (mandarin fish) ]

Gene ID: 122885629, updated on 22-Mar-2024

Summary

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Gene symbol
ifih1
Gene description
interferon induced with helicase C domain 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Siniperca chuatsi
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Eupercaria; Centrarchiformes; Centrarchoidei; Sinipercidae; Siniperca
Also known as
MDA5
Orthologs
human zebrafish all
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Genomic context

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See ifih1 in Genome Data Viewer
Location:
chromosome: LG12
Exon count:
16
Annotation release Status Assembly LG Location
100 current ASM2008510v1 (GCF_020085105.1) LG12 NC_058053.1 (13898140..13909504, complement)

Linkage Group LG12 - NC_058053.1Genomic Context describing neighboring genes Neighboring gene fibroblast activation protein, alpha Neighboring gene glucagon b Neighboring gene potassium voltage-gated channel subfamily H member 7-like Neighboring gene uncharacterized LOC122885834

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_058053.1 Chromosome LG12 Reference ASM2008510v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transcriptomic analysis of Mandarin fish brain cells infected with infectious spleen and kidney necrosis virus with an emphasis on retinoic acid-inducible gene 1-like receptors and apoptosis pathways. Hu X, et al. Fish Shellfish Immunol, 2015 Aug. PMID 25982401
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables double-stranded RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-stranded RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of interferon-beta production IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to virus IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
interferon-induced helicase C domain-containing protein 1
Names
melanoma differentiation-associated protein 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Siniperca chuatsi Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM2008510v1 Primary Assembly

Genomic

  1. NC_058053.1 Reference ASM2008510v1 Primary Assembly

    Range
    13898140..13909504 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_044216978.1 → XP_044072913.1  interferon-induced helicase C domain-containing protein 1

    UniProtKB/TrEMBL
    A0A0G2T6R5
    Conserved Domains (5) summary
    COG1111
    Location:289 → 815
    MPH1; ERCC4-related helicase [Replication, recombination and repair]
    cd08818
    Location:6 → 97
    CARD_MDA5_r1; Caspase activation and recruitment domain found in MDA5, first repeat
    cd08819
    Location:106 → 197
    CARD_MDA5_r2; Caspase activation and recruitment domain found in MDA5, second repeat
    cd15807
    Location:854 → 969
    MDA5_C; C-terminal domain of Melanoma differentiation-associated protein 5, a cytoplasmic viral RNA receptor
    cl28899
    Location:286 → 500
    DEAD-like_helicase_N; N-terminal helicase domain of the DEAD-box helicase superfamily
Nucleotide Protein
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