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lyn LYN proto-oncogene, Src family tyrosine kinase [ Gambusia affinis (western mosquitofish) ]

Gene ID: 122841534, updated on 28-May-2024

Summary

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Gene symbol
lyn
Gene description
LYN proto-oncogene, Src family tyrosine kinase
See related
EnsemblRapid:ENSGAFG00005005586
Gene type
protein coding
RefSeq status
MODEL
Organism
Gambusia affinis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae; Gambusia
Orthologs
human zebrafish all
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Genomic context

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See lyn in Genome Data Viewer
Location:
chromosome: LG12
Exon count:
13
Annotation release Status Assembly LG Location
100 current SWU_Gaff_1.0 (GCF_019740435.1) LG12 NC_057879.1 (6477956..6496218)

Linkage Group LG12 - NC_057879.1Genomic Context describing neighboring genes Neighboring gene ankyrin repeat domain 33Bb Neighboring gene catenin (cadherin-associated protein), delta 2b Neighboring gene cAMP-dependent protein kinase inhibitor alpha-like Neighboring gene uroporphyrinogen decarboxylase Neighboring gene zinc finger, SWIM-type containing 5

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_057879.1 Chromosome LG12 Reference SWU_Gaff_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extrinsic component of cytoplasmic side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein kinase Lyn

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gambusia affinis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference SWU_Gaff_1.0 Primary Assembly

Genomic

  1. NC_057879.1 Reference SWU_Gaff_1.0 Primary Assembly

    Range
    6477956..6496218
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_044134915.1 → XP_043990850.1  tyrosine-protein kinase Lyn

    Related
    ENSGAFP00005017517.1, ENSGAFT00005018064.1
    Conserved Domains (3) summary
    cl15255
    Location:122 → 222
    SH2; Src homology 2 (SH2) domain
    cl17036
    Location:64 → 119
    SH3; Src Homology 3 domain superfamily
    cl21453
    Location:236 → 506
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version

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