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capn3b calpain 3b [ Gambusia affinis (western mosquitofish) ]

Gene ID: 122825756, updated on 28-May-2024

Summary

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Gene symbol
capn3b
Gene description
calpain 3b
See related
EnsemblRapid:ENSGAFG00005007411
Gene type
protein coding
RefSeq status
MODEL
Organism
Gambusia affinis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae; Gambusia
Orthologs
zebrafish all
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Genomic context

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See capn3b in Genome Data Viewer
Location:
chromosome: LG22
Exon count:
23
Annotation release Status Assembly LG Location
100 current SWU_Gaff_1.0 (GCF_019740435.1) LG22 NC_057889.1 (8040155..8051116)

Linkage Group LG22 - NC_057889.1Genomic Context describing neighboring genes Neighboring gene Rh associated glycoprotein Neighboring gene macoilin-1 Neighboring gene nuclear receptor binding protein 1 Neighboring gene zinc finger protein 106-like Neighboring gene churchill domain containing 1 Neighboring gene tau tubulin kinase 2b

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_057889.1 Chromosome LG22 Reference SWU_Gaff_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium-dependent cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
calpain-3b

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gambusia affinis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference SWU_Gaff_1.0 Primary Assembly

Genomic

  1. NC_057889.1 Reference SWU_Gaff_1.0 Primary Assembly

    Range
    8040155..8051116
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_044107293.1 → XP_043963228.1  calpain-3b isoform X2

    UniProtKB/TrEMBL
    A0A315VVZ1
    Related
    ENSGAFP00005021044.1, ENSGAFT00005021600.1
    Conserved Domains (4) summary
    smart00230
    Location:64 → 382
    CysPc; Calpain-like thiol protease family
    cd00214
    Location:385 → 541
    Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...
    cd15897
    Location:602 → 630
    EFh_PEF; EF-hand motif [structural motif]
    cl25352
    Location:602 → 770
    EFh_PEF; The penta-EF hand (PEF) family

  2. XM_044107292.1 → XP_043963227.1  calpain-3b isoform X1

    UniProtKB/TrEMBL
    A0A315VVZ1
    Related
    ENSGAFP00005021021.1, ENSGAFT00005021577.1
    Conserved Domains (4) summary
    smart00230
    Location:64 → 382
    CysPc; Calpain-like thiol protease family
    cd00214
    Location:385 → 541
    Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...
    cd15897
    Location:603 → 631
    EFh_PEF; EF-hand motif [structural motif]
    cl25352
    Location:603 → 771
    EFh_PEF; The penta-EF hand (PEF) family
Nucleotide Protein
Heading Accession and Version

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