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ARHGAP12 Rho GTPase activating protein 12 [ Cervus elaphus (red deer) ]

Gene ID: 122681273, updated on 22-Mar-2024

Summary

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Gene symbol
ARHGAP12
Gene description
Rho GTPase activating protein 12
See related
EnsemblRapid:ENSCESG00005010951
Gene type
protein coding
RefSeq status
MODEL
Organism
Cervus elaphus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Cervidae; Cervinae; Cervus
Orthologs
human mouse all
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Genomic context

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See ARHGAP12 in Genome Data Viewer
Location:
chromosome: 23
Exon count:
19
Annotation release Status Assembly Chr Location
100 current mCerEla1.1 (GCF_910594005.1) 23 NC_057837.1 (33735725..33851574)

Chromosome 23 - NC_057837.1Genomic Context describing neighboring genes Neighboring gene kinesin family member 5B Neighboring gene U6 spliceosomal RNA Neighboring gene translation initiation factor IF-2-like Neighboring gene uncharacterized LOC122681703 Neighboring gene uncharacterized LOC122682040

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_057837.1 Chromosome 23 Reference mCerEla1.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rho GTPase-activating protein 12

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cervus elaphus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCerEla1.1

Genomic

  1. NC_057837.1 Reference mCerEla1.1

    Range
    33735725..33851574
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_043883168.1 → XP_043739103.1  rho GTPase-activating protein 12 isoform X1

    Conserved Domains (5) summary
    cd12070
    Location:15 → 74
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:260 → 413
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:269 → 299
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd04403
    Location:650 → 835
    RhoGAP_ARHGAP27_15_12_9; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. Most members that are ...
    cd13233
    Location:461 → 572
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain

  2. XM_043883167.1 → XP_043739102.1  rho GTPase-activating protein 12 isoform X1

    Conserved Domains (5) summary
    cd12070
    Location:15 → 74
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:260 → 413
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:269 → 299
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd04403
    Location:650 → 835
    RhoGAP_ARHGAP27_15_12_9; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. Most members that are ...
    cd13233
    Location:461 → 572
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain

  3. XM_043883165.1 → XP_043739100.1  rho GTPase-activating protein 12 isoform X1

    Related
    ENSCESP00005014409.1, ENSCEST00005017045.1
    Conserved Domains (5) summary
    cd12070
    Location:15 → 74
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:260 → 413
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:269 → 299
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd04403
    Location:650 → 835
    RhoGAP_ARHGAP27_15_12_9; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. Most members that are ...
    cd13233
    Location:461 → 572
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain

  4. XM_043883170.1 → XP_043739105.1  rho GTPase-activating protein 12 isoform X2

    Related
    ENSCESP00005014413.1, ENSCEST00005017048.1
    Conserved Domains (5) summary
    cd12070
    Location:15 → 74
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:260 → 413
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:269 → 299
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd04403
    Location:625 → 810
    RhoGAP_ARHGAP27_15_12_9; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. Most members that are ...
    cd13233
    Location:436 → 547
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain

  5. XM_043883171.1 → XP_043739106.1  rho GTPase-activating protein 12 isoform X3

    Related
    ENSCESP00005014394.1, ENSCEST00005017030.1
    Conserved Domains (5) summary
    cd12070
    Location:15 → 74
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:260 → 366
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:269 → 299
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd04403
    Location:603 → 788
    RhoGAP_ARHGAP27_15_12_9; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. Most members that are ...
    cd13233
    Location:414 → 525
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain

  6. XM_043883173.1 → XP_043739108.1  rho GTPase-activating protein 12 isoform X4

    Conserved Domains (5) summary
    cd12070
    Location:15 → 74
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:260 → 366
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:269 → 299
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd04403
    Location:578 → 763
    RhoGAP_ARHGAP27_15_12_9; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. Most members that are ...
    cd13233
    Location:389 → 500
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain

  7. XM_043883174.1 → XP_043739109.1  rho GTPase-activating protein 12 isoform X5

    Conserved Domains (3) summary
    cd12070
    Location:15 → 74
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    cd04403
    Location:515 → 700
    RhoGAP_ARHGAP27_15_12_9; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. Most members that are ...
    cd13233
    Location:326 → 437
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain

  8. XM_043883166.1 → XP_043739101.1  rho GTPase-activating protein 12 isoform X1

    Conserved Domains (5) summary
    cd12070
    Location:15 → 74
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:260 → 413
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:269 → 299
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd04403
    Location:650 → 835
    RhoGAP_ARHGAP27_15_12_9; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. Most members that are ...
    cd13233
    Location:461 → 572
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain

  9. XM_043883169.1 → XP_043739104.1  rho GTPase-activating protein 12 isoform X1

    Conserved Domains (5) summary
    cd12070
    Location:15 → 74
    SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
    COG5104
    Location:260 → 413
    PRP40; Splicing factor [RNA processing and modification]
    cd00201
    Location:269 → 299
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd04403
    Location:650 → 835
    RhoGAP_ARHGAP27_15_12_9; GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. Most members that are ...
    cd13233
    Location:461 → 572
    PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
Nucleotide Protein
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