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cbl Cbl proto-oncogene, E3 ubiquitin protein ligase [ Puntigrus tetrazona (Sumatra barb) ]

Gene ID: 122359556, updated on 8-May-2024

Summary

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Gene symbol
cbl
Gene description
Cbl proto-oncogene, E3 ubiquitin protein ligase
See related
EnsemblRapid:ENSPRZG00000031455
Gene type
protein coding
RefSeq status
MODEL
Organism
Puntigrus tetrazona
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Cyprinidae; Smiliogastrinae; Puntigrus
Orthologs
human zebrafish all
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Genomic context

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See cbl in Genome Data Viewer
Location:
chromosome: 15
Exon count:
16
Annotation release Status Assembly Chr Location
100 current ASM1883169v1 (GCF_018831695.1) 15 NC_056713.1 (13226503..13251217)

Chromosome 15 - NC_056713.1Genomic Context describing neighboring genes Neighboring gene glutamate receptor, ionotropic, kainate 4 Neighboring gene dynein regulatory complex subunit 12 homolog Neighboring gene melanoma cell adhesion molecule b Neighboring gene ring finger protein 26

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056713.1 Chromosome 15 Reference ASM1883169v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables SH3 domain binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphotyrosine residue binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables receptor tyrosine kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of epidermal growth factor-activated receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane raft IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase CBL

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Puntigrus tetrazona Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1883169v1 Primary Assembly

Genomic

  1. NC_056713.1 Reference ASM1883169v1 Primary Assembly

    Range
    13226503..13251217
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_043259891.1 → XP_043115826.1  E3 ubiquitin-protein ligase CBL isoform X2

    Related
    ENSPRZP00000066240.1, ENSPRZT00000076115.1
    Conserved Domains (4) summary
    cd09920
    Location:240 → 336
    SH2_Cbl-b_TKB; Src homology 2 (SH2) domain found in the Cbl-b TKB domain
    PHA03247
    Location:495 → 849
    PHA03247; large tegument protein UL36; Provisional
    cd14393
    Location:862 → 901
    UBA_c-Cbl; UBA domain found in E3 ubiquitin-protein ligase Cbl and similar proteins
    cd16709
    Location:346 → 411
    RING-HC_Cbl-b; RING finger, HC subclass, found in E3 ubiquitin-protein ligase Cbl-b and similar proteins

  2. XM_043259890.1 → XP_043115825.1  E3 ubiquitin-protein ligase CBL isoform X1

    Related
    ENSPRZP00000066244.1, ENSPRZT00000076119.1
    Conserved Domains (4) summary
    cd09920
    Location:240 → 336
    SH2_Cbl-b_TKB; Src homology 2 (SH2) domain found in the Cbl-b TKB domain
    PHA03247
    Location:495 → 850
    PHA03247; large tegument protein UL36; Provisional
    cd14393
    Location:863 → 902
    UBA_c-Cbl; UBA domain found in E3 ubiquitin-protein ligase Cbl and similar proteins
    cd16709
    Location:346 → 411
    RING-HC_Cbl-b; RING finger, HC subclass, found in E3 ubiquitin-protein ligase Cbl-b and similar proteins
Nucleotide Protein
Heading Accession and Version

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