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hic1 hypermethylated in cancer 1 [ Plectropomus leopardus (leopard coralgrouper) ]

Gene ID: 121943805, updated on 22-Mar-2024

Summary

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Gene symbol
hic1
Gene description
hypermethylated in cancer 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Plectropomus leopardus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Eupercaria; Perciformes; Serranoidei; Serranidae; Epinephelinae; Epinephelini; Plectropomus
Orthologs
human zebrafish all
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Genomic context

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See hic1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
3
Annotation release Status Assembly Chr Location
100 current YSFRI_Pleo_2.0 (GCF_008729295.1) 5 NC_056467.1 (22889655..22903726)

Chromosome 5 - NC_056467.1Genomic Context describing neighboring genes Neighboring gene TAO kinase 1a Neighboring gene TSR1 ribosome maturation factor Neighboring gene diphthamide biosynthesis 1 Neighboring gene reticulon 4 receptor-like 1b

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056467.1 Chromosome 5 Reference YSFRI_Pleo_2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hypermethylated in cancer 1 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Plectropomus leopardus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference YSFRI_Pleo_2.0 Primary Assembly

Genomic

  1. NC_056467.1 Reference YSFRI_Pleo_2.0 Primary Assembly

    Range
    22889655..22903726
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042487423.1 → XP_042343357.1  hypermethylated in cancer 1 protein isoform X1

    Conserved Domains (4) summary
    smart00355
    Location:583 → 605
    ZnF_C2H2; zinc finger
    COG5048
    Location:609 → 657
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:585 → 605
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18333
    Location:38 → 160
    BTB_POZ_ZBTB29_HIC1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in hypermethylated in cancer 1 protein (Hic-1)

  2. XM_042487426.1 → XP_042343360.1  hypermethylated in cancer 1 protein isoform X4

    Conserved Domains (3) summary
    smart00355
    Location:552 → 574
    ZnF_C2H2; zinc finger
    sd00017
    Location:554 → 574
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18333
    Location:7 → 129
    BTB_POZ_ZBTB29_HIC1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in hypermethylated in cancer 1 protein (Hic-1)

  3. XM_042487425.1 → XP_042343359.1  hypermethylated in cancer 1 protein isoform X3

    Conserved Domains (4) summary
    smart00355
    Location:565 → 587
    ZnF_C2H2; zinc finger
    COG5048
    Location:591 → 639
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:567 → 587
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18333
    Location:20 → 142
    BTB_POZ_ZBTB29_HIC1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in hypermethylated in cancer 1 protein (Hic-1)

  4. XM_042487424.1 → XP_042343358.1  hypermethylated in cancer 1 protein isoform X2

    Conserved Domains (4) summary
    smart00355
    Location:575 → 597
    ZnF_C2H2; zinc finger
    COG5048
    Location:601 → 649
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:577 → 597
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18333
    Location:30 → 152
    BTB_POZ_ZBTB29_HIC1; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in hypermethylated in cancer 1 protein (Hic-1)
Nucleotide Protein
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