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SFRP1 secreted frizzled related protein 1 [ Sceloporus undulatus (fence lizard) ]

Gene ID: 121935616, updated on 22-Mar-2024

Summary

Gene symbol
SFRP1
Gene description
secreted frizzled related protein 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Sceloporus undulatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Iguania; Phrynosomatidae; Phrynosomatinae; Sceloporus
Orthologs
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Genomic context

See SFRP1 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
4
Annotation release Status Assembly Chr Location
100 current SceUnd_v1.1 (GCF_019175285.1) 6 NC_056527.1 (122845637..122867987)

Chromosome 6 - NC_056527.1Genomic Context describing neighboring genes Neighboring gene GINS complex subunit 4 Neighboring gene golgin A7 Neighboring gene zinc finger matrin-type 4 Neighboring gene transcriptional and immune response regulator

Genomic regions, transcripts, and products

Genomic Sequence:
NC_056527.1 Chromosome 6 Reference SceUnd_v1.1

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Wnt-protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in non-canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
secreted frizzled-related protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Sceloporus undulatus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference SceUnd_v1.1

Genomic

  1. NC_056527.1 Reference SceUnd_v1.1

    Range
    122845637..122867987
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042477332.1XP_042333266.1  secreted frizzled-related protein 1

    Conserved Domains (2) summary
    cd07443
    Location:59182
    CRD_SFRP1; Cysteine-rich domain of the secreted frizzled-related protein 1 (SFRP1), a regulator of Wnt activity
    cd03580
    Location:190297
    NTR_Sfrp1_like; NTR domain, Secreted frizzled-related protein (Sfrp) 1-like subfamily; composed of proteins similar to human Sfrp1, Sfrp2 and Sfrp5. Sfrps are soluble proteins containing an NTR domain C-terminal to a cysteine-rich Frizzled domain. They show diverse ...