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Hmgcr HMG coenzyme A reductase [ Homarus americanus (American lobster) ]

Gene ID: 121862368, updated on 3-Jul-2024

Summary

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Gene symbol
Hmgcr
Gene description
HMG coenzyme A reductase
Locus tag
Hamer_G000864
See related
EnsemblRapid:LOC121862368
Gene type
protein coding
RefSeq status
MODEL
Organism
Homarus americanus
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Multicrustacea; Malacostraca; Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Astacidea; Nephropoidea; Nephropidae; Homarus
Also known as
HMGR1; HMGR2; HMGCR-L
Orthologs
fruit fly all
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Genomic context

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See Hmgcr in Genome Data Viewer
Location:
chromosome: Un
Exon count:
18
Annotation release Status Assembly Chr Location
100 current GMGI_Hamer_2.0 (GCF_018991925.1) Unplaced Scaffold NW_024722227.1 (9110305..9239560, complement)

NW_024722227.1Genomic Context describing neighboring genes Neighboring gene dehydrogenase/reductase SDR family member 11-like Neighboring gene mitochondrial ribosomal protein S21 Neighboring gene cysteine--tRNA ligase, cytoplasmic-like Neighboring gene U-scoloptoxin(01)-Er1a-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_024722227 Unplaced Scaffold Reference GMGI_Hamer_2.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The lobster mandibular organ produces soluble and membrane-bound forms of 3-hydroxy-3-methylglutaryl-CoA reductase. Li S, et al. Biochem J, 2004 Aug 1. PMID 15086315, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NADP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables hydroxymethylglutaryl-CoA reductase (NADPH) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in coenzyme A metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in isoprenoid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sterol biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in peroxisomal membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
3-hydroxy-3-methylglutaryl-coenzyme A reductase-like
Names
one-transmembrane-helix HMG-CoA reductase
soluble HMG-CoA reductase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Homarus americanus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GMGI_Hamer_2.0 Primary Assembly

Genomic

  1. NW_024722227.1 Reference GMGI_Hamer_2.0 Primary Assembly

    Range
    9110305..9239560 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042360617.1 → XP_042216551.1  3-hydroxy-3-methylglutaryl-coenzyme A reductase-like isoform X1

    UniProtKB/TrEMBL
    A0A8J5N2A0
    Related
    XP_042216551.1, XM_042360617.1
    Conserved Domains (1) summary
    TIGR00920
    Location:11 → 862
    2A060605; 3-hydroxy-3-methylglutaryl-coenzyme A reductase

  2. XM_042360618.1 → XP_042216552.1  3-hydroxy-3-methylglutaryl-coenzyme A reductase-like isoform X2

    UniProtKB/TrEMBL
    A0A8J5N2A0
    Related
    XP_042216552.1, XM_042360618.1
    Conserved Domains (1) summary
    TIGR00920
    Location:11 → 862
    2A060605; 3-hydroxy-3-methylglutaryl-coenzyme A reductase
Nucleotide Protein
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