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JAK2 Janus kinase 2 [ Corvus kubaryi (Mariana crow) ]

Gene ID: 121676913, updated on 3-Aug-2024

Summary

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Gene symbol
JAK2
Gene description
Janus kinase 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Corvus kubaryi
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Passeriformes; Corvoidea; Corvidae; Corvus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
28
Annotation release Status Assembly Chr Location
100 current C.kubaryi_AGA036_p1.0 (GCF_017639235.1) Unplaced Scaffold NW_024582075.1 (17042816..17138347, complement)

NW_024582075.1Genomic Context describing neighboring genes Neighboring gene relaxin-3-like Neighboring gene plasminogen receptor with a C-terminal lysine Neighboring gene uncharacterized LOC121657317 Neighboring gene uncharacterized LOC121657316 Neighboring gene RNA terminal phosphate cyclase like 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_024582075 Unplaced Scaffold Reference C.kubaryi_AGA036_p1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cytokine receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in hemopoiesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-tyrosine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein kinase JAK2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Corvus kubaryi Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference C.kubaryi_AGA036_p1.0

Genomic

  1. NW_024582075.1 Reference C.kubaryi_AGA036_p1.0

    Range
    17042816..17138347 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042053969.1 → XP_041909903.1  tyrosine-protein kinase JAK2 isoform X2

    Conserved Domains (5) summary
    cd10379
    Location:384 → 480
    SH2_Jak2; Src homology 2 (SH2) domain in the Janus kinase 2 (Jak2) proteins
    smart00295
    Location:37 → 268
    B41; Band 4.1 homologues
    cd13333
    Location:264 → 384
    FERM_C_JAK2; FERM domain C-lobe of Janus kinase (JAK) 2
    cd05078
    Location:543 → 804
    PTK_Jak2_rpt1; Pseudokinase (repeat 1) domain of the Protein Tyrosine Kinase, Janus kinase 2
    cl21453
    Location:846 → 1020
    PKc_like; Protein Kinases, catalytic domain

  2. XM_042053964.1 → XP_041909898.1  tyrosine-protein kinase JAK2 isoform X1

    Conserved Domains (6) summary
    cd10379
    Location:384 → 480
    SH2_Jak2; Src homology 2 (SH2) domain in the Janus kinase 2 (Jak2) proteins
    cd13333
    Location:264 → 384
    FERM_C_JAK2; FERM domain C-lobe of Janus kinase (JAK) 2
    cd05078
    Location:543 → 804
    PTK_Jak2_rpt1; Pseudokinase (repeat 1) domain of the Protein Tyrosine Kinase, Janus kinase 2
    cd14205
    Location:842 → 1125
    PTKc_Jak2_rpt2; Catalytic (repeat 2) domain of the Protein Tyrosine Kinase, Janus kinase 2
    pfam18377
    Location:140 → 259
    FERM_F2; FERM F2 acyl-CoA binding protein-like domain
    pfam18379
    Location:37 → 132
    FERM_F1; FERM F1 ubiquitin-like domain

  3. XM_042053968.1 → XP_041909902.1  tyrosine-protein kinase JAK2 isoform X1

    Conserved Domains (6) summary
    cd10379
    Location:384 → 480
    SH2_Jak2; Src homology 2 (SH2) domain in the Janus kinase 2 (Jak2) proteins
    cd13333
    Location:264 → 384
    FERM_C_JAK2; FERM domain C-lobe of Janus kinase (JAK) 2
    cd05078
    Location:543 → 804
    PTK_Jak2_rpt1; Pseudokinase (repeat 1) domain of the Protein Tyrosine Kinase, Janus kinase 2
    cd14205
    Location:842 → 1125
    PTKc_Jak2_rpt2; Catalytic (repeat 2) domain of the Protein Tyrosine Kinase, Janus kinase 2
    pfam18377
    Location:140 → 259
    FERM_F2; FERM F2 acyl-CoA binding protein-like domain
    pfam18379
    Location:37 → 132
    FERM_F1; FERM F1 ubiquitin-like domain

  4. XM_042053966.1 → XP_041909900.1  tyrosine-protein kinase JAK2 isoform X1

    Conserved Domains (6) summary
    cd10379
    Location:384 → 480
    SH2_Jak2; Src homology 2 (SH2) domain in the Janus kinase 2 (Jak2) proteins
    cd13333
    Location:264 → 384
    FERM_C_JAK2; FERM domain C-lobe of Janus kinase (JAK) 2
    cd05078
    Location:543 → 804
    PTK_Jak2_rpt1; Pseudokinase (repeat 1) domain of the Protein Tyrosine Kinase, Janus kinase 2
    cd14205
    Location:842 → 1125
    PTKc_Jak2_rpt2; Catalytic (repeat 2) domain of the Protein Tyrosine Kinase, Janus kinase 2
    pfam18377
    Location:140 → 259
    FERM_F2; FERM F2 acyl-CoA binding protein-like domain
    pfam18379
    Location:37 → 132
    FERM_F1; FERM F1 ubiquitin-like domain

  5. XM_042053967.1 → XP_041909901.1  tyrosine-protein kinase JAK2 isoform X1

    Conserved Domains (6) summary
    cd10379
    Location:384 → 480
    SH2_Jak2; Src homology 2 (SH2) domain in the Janus kinase 2 (Jak2) proteins
    cd13333
    Location:264 → 384
    FERM_C_JAK2; FERM domain C-lobe of Janus kinase (JAK) 2
    cd05078
    Location:543 → 804
    PTK_Jak2_rpt1; Pseudokinase (repeat 1) domain of the Protein Tyrosine Kinase, Janus kinase 2
    cd14205
    Location:842 → 1125
    PTKc_Jak2_rpt2; Catalytic (repeat 2) domain of the Protein Tyrosine Kinase, Janus kinase 2
    pfam18377
    Location:140 → 259
    FERM_F2; FERM F2 acyl-CoA binding protein-like domain
    pfam18379
    Location:37 → 132
    FERM_F1; FERM F1 ubiquitin-like domain
Nucleotide Protein
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