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ALOX12B arachidonate 12-lipoxygenase, 12R type [ Vulpes lagopus (Arctic fox) ]

Gene ID: 121500377, updated on 22-Mar-2024

Summary

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Gene symbol
ALOX12B
Gene description
arachidonate 12-lipoxygenase, 12R type
Gene type
protein coding
RefSeq status
MODEL
Organism
Vulpes lagopus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes
Orthologs
human mouse all
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Genomic context

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See ALOX12B in Genome Data Viewer
Location:
chromosome: 10
Exon count:
15
Annotation release Status Assembly Chr Location
100 current ASM1834538v1 (GCF_018345385.1) 10 NC_054833.1 (59273871..59285524, complement)

Chromosome 10 - NC_054833.1Genomic Context describing neighboring genes Neighboring gene guanylate cyclase 2D, retinal Neighboring gene arachidonate 15-lipoxygenase type B Neighboring gene arachidonate epidermal lipoxygenase 3 Neighboring gene transfer RNA lysine (anticodon UUU)

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_054833.1 Chromosome 10 Reference ASM1834538v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables arachidonate 12(S)-lipoxygenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables iron ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in linoleic acid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid oxidation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
arachidonate 12-lipoxygenase, 12R-type

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Vulpes lagopus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1834538v1 Primary Assembly

Genomic

  1. NC_054833.1 Reference ASM1834538v1 Primary Assembly

    Range
    59273871..59285524 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041772047.1 → XP_041627981.1  arachidonate 12-lipoxygenase, 12R-type

    Conserved Domains (2) summary
    PLN02337
    Location:256 → 699
    PLN02337; lipoxygenase
    cd01753
    Location:2 → 116
    PLAT_LOX; PLAT domain of 12/15-lipoxygenase. As a unique subfamily of the mammalian lipoxygenases, they catalyze enzymatic lipid peroxidation in complex biological structures via direct dioxygenation of phospholipids and cholesterol esters of biomembranes and ...
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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