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PKM pyruvate kinase M1/2 [ Vulpes lagopus (Arctic fox) ]

Gene ID: 121484558, updated on 22-Mar-2024

Summary

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Gene symbol
PKM
Gene description
pyruvate kinase M1/2
Gene type
protein coding
RefSeq status
MODEL
Organism
Vulpes lagopus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes
Orthologs
human mouse all
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Genomic context

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See PKM in Genome Data Viewer
Location:
chromosome: 2
Exon count:
12
Annotation release Status Assembly Chr Location
100 current ASM1834538v1 (GCF_018345385.1) 2 NC_054825.1 (45954633..45981050)

Chromosome 2 - NC_054825.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121484947 Neighboring gene poly(ADP-ribose) polymerase family member 6 Neighboring gene GRAM domain containing 2A Neighboring gene SUMO peptidase family member, NEDD8 specific Neighboring gene myosin IXA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_054825.1 Chromosome 2 Reference ASM1834538v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables potassium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables pyruvate kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to insulin stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glycolytic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
pyruvate kinase PKM

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Vulpes lagopus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1834538v1 Primary Assembly

Genomic

  1. NC_054825.1 Reference ASM1834538v1 Primary Assembly

    Range
    45954633..45981050
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041743963.1 → XP_041599897.1  pyruvate kinase PKM isoform X2

    Conserved Domains (1) summary
    cd00288
    Location:42 → 530
    Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...

  2. XM_041743962.1 → XP_041599896.1  pyruvate kinase PKM isoform X1

    Conserved Domains (1) summary
    cd00288
    Location:42 → 530
    Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...
Nucleotide Protein Strain
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