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MASP1 MBL associated serine protease 1 [ Vulpes lagopus (Arctic fox) ]

Gene ID: 121477498, updated on 22-Mar-2024

Summary

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Gene symbol
MASP1
Gene description
MBL associated serine protease 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Vulpes lagopus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Vulpes
Orthologs
human mouse all
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Genomic context

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See MASP1 in Genome Data Viewer
Location:
chromosome: 17
Exon count:
18
Annotation release Status Assembly Chr Location
100 current ASM1834538v1 (GCF_018345385.1) 17 NC_054840.1 (22381464..22442632)

Chromosome 17 - NC_054840.1Genomic Context describing neighboring genes Neighboring gene somatostatin Neighboring gene receptor transporter protein 4 Neighboring gene uncharacterized LOC121477499 Neighboring gene receptor transporter protein 1 Neighboring gene ST6 beta-galactoside alpha-2,6-sialyltransferase 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_054840.1 Chromosome 17 Reference ASM1834538v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in complement activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in zymogen activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in blood microparticle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mannan-binding lectin serine protease 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Vulpes lagopus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1834538v1 Primary Assembly

Genomic

  1. NC_054840.1 Reference ASM1834538v1 Primary Assembly

    Range
    22381464..22442632
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041731870.1 → XP_041587804.1  mannan-binding lectin serine protease 1 isoform X1

    Conserved Domains (5) summary
    cd00033
    Location:301 → 363
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    PHA02639
    Location:300 → 433
    PHA02639; EEV host range protein; Provisional
    smart00020
    Location:449 → 710
    Tryp_SPc; Trypsin-like serine protease
    smart00179
    Location:139 → 181
    EGF_CA; Calcium-binding EGF-like domain
    cd00041
    Location:185 → 296
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.

  2. XM_041731871.1 → XP_041587805.1  mannan-binding lectin serine protease 1 isoform X2

    Conserved Domains (5) summary
    cd00033
    Location:301 → 363
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    PHA02639
    Location:300 → 433
    PHA02639; EEV host range protein; Provisional
    smart00020
    Location:449 → 710
    Tryp_SPc; Trypsin-like serine protease
    smart00179
    Location:139 → 181
    EGF_CA; Calcium-binding EGF-like domain
    cd00041
    Location:185 → 296
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.

  3. XM_041731873.1 → XP_041587807.1  mannan-binding lectin serine protease 1 isoform X4

    Conserved Domains (3) summary
    cd00033
    Location:301 → 363
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    smart00179
    Location:139 → 181
    EGF_CA; Calcium-binding EGF-like domain
    cd00041
    Location:185 → 296
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.

  4. XM_041731872.1 → XP_041587806.1  mannan-binding lectin serine protease 1 isoform X3

    Conserved Domains (5) summary
    cd00033
    Location:303 → 365
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    PHA02639
    Location:302 → 435
    PHA02639; EEV host range protein; Provisional
    smart00179
    Location:141 → 183
    EGF_CA; Calcium-binding EGF-like domain
    cd00041
    Location:187 → 298
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00190
    Location:451 → 696
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
Nucleotide Protein Strain
Heading Accession and Version

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