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Tjp2 tight junction protein 2 [ Microtus oregoni (creeping vole) ]

Gene ID: 121453838, updated on 22-Mar-2024

Summary

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Gene symbol
Tjp2
Gene description
tight junction protein 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Microtus oregoni
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Arvicolinae; Microtus
Orthologs
human mouse all
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Genomic context

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See Tjp2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
27
Annotation release Status Assembly Chr Location
100 current Mior012 (GCF_018167655.1) Unplaced Scaffold NW_024543071.1 (35499276..35626642)

NW_024543071.1Genomic Context describing neighboring genes Neighboring gene phosphatidylinositol-4-phosphate 5-kinase type 1 beta Neighboring gene PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1 Neighboring gene frataxin Neighboring gene uncharacterized LOC121453837 Neighboring gene E3 ubiquitin-protein ligase NRDP1-like Neighboring gene endosomal transmembrane epsin interactor 1 Neighboring gene amyloid beta precursor protein binding family A member 1 Neighboring gene 60S ribosomal protein L22-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_024543071 Unplaced Scaffold Reference Mior012

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell junction organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment of endothelial intestinal barrier IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of blood-brain barrier permeability IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to cell-cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tight junction protein ZO-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Microtus oregoni Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mior012

Genomic

  1. NW_024543071.1 Reference Mior012

    Range
    35499276..35626642
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041660776.1 → XP_041516710.1  tight junction protein ZO-2 isoform X4

    Conserved Domains (4) summary
    cd12027
    Location:582 → 644
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:678 → 857
    GuKc; Guanylate kinase homologues
    smart00228
    Location:286 → 363
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  2. XM_041660777.1 → XP_041516711.1  tight junction protein ZO-2 isoform X4

    Conserved Domains (4) summary
    cd12027
    Location:582 → 644
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:678 → 857
    GuKc; Guanylate kinase homologues
    smart00228
    Location:286 → 363
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  3. XM_041660780.1 → XP_041516714.1  tight junction protein ZO-2 isoform X7

    Conserved Domains (4) summary
    cd12027
    Location:605 → 667
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:701 → 880
    GuKc; Guanylate kinase homologues
    smart00228
    Location:309 → 386
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:32 → 117
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  4. XM_041660775.1 → XP_041516709.1  tight junction protein ZO-2 isoform X3

    Conserved Domains (4) summary
    cd12027
    Location:605 → 667
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:701 → 880
    GuKc; Guanylate kinase homologues
    smart00228
    Location:309 → 386
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:32 → 117
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  5. XM_041660778.1 → XP_041516712.1  tight junction protein ZO-2 isoform X5

    Conserved Domains (4) summary
    cd12027
    Location:613 → 675
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:709 → 888
    GuKc; Guanylate kinase homologues
    smart00228
    Location:317 → 394
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:40 → 125
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  6. XM_041660773.1 → XP_041516707.1  tight junction protein ZO-2 isoform X1

    Conserved Domains (4) summary
    cd12027
    Location:613 → 675
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:709 → 888
    GuKc; Guanylate kinase homologues
    smart00228
    Location:317 → 394
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:40 → 125
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  7. XM_041660774.1 → XP_041516708.1  tight junction protein ZO-2 isoform X2

    Conserved Domains (4) summary
    cd12027
    Location:609 → 671
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:705 → 884
    GuKc; Guanylate kinase homologues
    smart00228
    Location:313 → 390
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:36 → 121
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  8. XM_041660779.1 → XP_041516713.1  tight junction protein ZO-2 isoform X6

    Conserved Domains (4) summary
    cd12027
    Location:609 → 671
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:705 → 884
    GuKc; Guanylate kinase homologues
    smart00228
    Location:313 → 390
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:36 → 121
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
Nucleotide Protein
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