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TDP2 tyrosyl-DNA phosphodiesterase 2 [ Bufo bufo (common toad) ]

Gene ID: 121001708, updated on 22-Mar-2024

Summary

Gene symbol
TDP2
Gene description
tyrosyl-DNA phosphodiesterase 2
See related
EnsemblRapid:ENSBBFG00005010091
Gene type
protein coding
RefSeq status
MODEL
Organism
Bufo bufo
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Neobatrachia; Hyloidea; Bufonidae; Bufo
Orthologs
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Genomic context

See TDP2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
7
Annotation release Status Assembly Chr Location
100 current aBufBuf1.1 (GCF_905171765.1) 5 NC_053393.1 (400222205..400258663, complement)

Chromosome 5 - NC_053393.1Genomic Context describing neighboring genes Neighboring gene aldehyde dehydrogenase 5 family member A1 Neighboring gene uncharacterized LOC121001714 Neighboring gene KIAA0319 ortholog Neighboring gene acyl-coenzyme A thioesterase 13-like Neighboring gene acyl-CoA thioesterase 13

Genomic regions, transcripts, and products

Genomic Sequence:
NC_053393.1 Chromosome 5 Reference aBufBuf1.1

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 5'-tyrosyl-DNA phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables single-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in double-strand break repair IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in PML body IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
tyrosyl-DNA phosphodiesterase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bufo bufo Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference aBufBuf1.1

Genomic

  1. NC_053393.1 Reference aBufBuf1.1

    Range
    400222205..400258663 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040432892.1XP_040288826.1  tyrosyl-DNA phosphodiesterase 2 isoform X3

    Conserved Domains (2) summary
    cd09080
    Location:115302
    TDP2; Phosphodiesterase domain of human TDP2, a 5'-tyrosyl DNA phosphodiesterase, and related domains
    cd14344
    Location:1854
    UBA_TYDP2; UBA-like domain found in tyrosyl-DNA phosphodiesterase 2 (TDP2) and similar proteins
  2. XM_040432889.1XP_040288823.1  tyrosyl-DNA phosphodiesterase 2 isoform X1

    Related
    ENSBBFP00005014902.1, ENSBBFT00005015812.1
    Conserved Domains (2) summary
    cd09080
    Location:115359
    TDP2; Phosphodiesterase domain of human TDP2, a 5'-tyrosyl DNA phosphodiesterase, and related domains
    cd14344
    Location:1854
    UBA_TYDP2; UBA-like domain found in tyrosyl-DNA phosphodiesterase 2 (TDP2) and similar proteins
  3. XM_040432891.1XP_040288825.1  tyrosyl-DNA phosphodiesterase 2 isoform X2

    Conserved Domains (1) summary
    cd09080
    Location:77321
    TDP2; Phosphodiesterase domain of human TDP2, a 5'-tyrosyl DNA phosphodiesterase, and related domains