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TJP2 tight junction protein 2 [ Bufo bufo (common toad) ]

Gene ID: 120989172, updated on 21-Mar-2024

Summary

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Gene symbol
TJP2
Gene description
tight junction protein 2
See related
EnsemblRapid:ENSBBFG00005004648
Gene type
protein coding
RefSeq status
MODEL
Organism
Bufo bufo
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Neobatrachia; Hyloidea; Bufonidae; Bufo
Orthologs
human mouse all
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Genomic context

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See TJP2 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
26
Annotation release Status Assembly Chr Location
100 current aBufBuf1.1 (GCF_905171765.1) 2 NC_053390.1 (351507481..351680958, complement)

Chromosome 2 - NC_053390.1Genomic Context describing neighboring genes Neighboring gene amyloid beta precursor protein binding family A member 1 Neighboring gene endosomal transmembrane epsin interactor 1 Neighboring gene tight junction protein ZO-2-like Neighboring gene frataxin

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_053390.1 Chromosome 2 Reference aBufBuf1.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell junction organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment of endothelial intestinal barrier IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of blood-brain barrier permeability IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to cell-cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tight junction protein ZO-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bufo bufo Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference aBufBuf1.1

Genomic

  1. NC_053390.1 Reference aBufBuf1.1

    Range
    351507481..351680958 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040417095.1 → XP_040273029.1  tight junction protein ZO-2 isoform X2

    Conserved Domains (5) summary
    smart00072
    Location:691 → 858
    GuKc; Guanylate kinase homologues
    PHA03247
    Location:1010 → 1124
    PHA03247; large tegument protein UL36; Provisional
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01622
    Location:157 → 265
    SF-CC1; splicing factor, CC1-like family
    cl17036
    Location:582 → 644
    SH3; Src Homology 3 domain superfamily

  2. XM_040417094.1 → XP_040273028.1  tight junction protein ZO-2 isoform X2

    Related
    ENSBBFP00005006925.1, ENSBBFT00005007339.1
    Conserved Domains (5) summary
    smart00072
    Location:691 → 858
    GuKc; Guanylate kinase homologues
    PHA03247
    Location:1010 → 1124
    PHA03247; large tegument protein UL36; Provisional
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01622
    Location:157 → 265
    SF-CC1; splicing factor, CC1-like family
    cl17036
    Location:582 → 644
    SH3; Src Homology 3 domain superfamily

  3. XM_040417093.1 → XP_040273027.1  tight junction protein ZO-2 isoform X1

    Related
    ENSBBFP00005006970.1, ENSBBFT00005007386.1
    Conserved Domains (5) summary
    smart00072
    Location:719 → 886
    GuKc; Guanylate kinase homologues
    PHA03247
    Location:1038 → 1152
    PHA03247; large tegument protein UL36; Provisional
    cd00992
    Location:37 → 122
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01622
    Location:185 → 293
    SF-CC1; splicing factor, CC1-like family
    cl17036
    Location:610 → 672
    SH3; Src Homology 3 domain superfamily

  4. XM_040417096.1 → XP_040273030.1  tight junction protein ZO-2 isoform X2

    Related
    ENSBBFP00005006938.1, ENSBBFT00005007352.1
    Conserved Domains (5) summary
    smart00072
    Location:691 → 858
    GuKc; Guanylate kinase homologues
    PHA03247
    Location:1010 → 1124
    PHA03247; large tegument protein UL36; Provisional
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01622
    Location:157 → 265
    SF-CC1; splicing factor, CC1-like family
    cl17036
    Location:582 → 644
    SH3; Src Homology 3 domain superfamily
Nucleotide Protein
Heading Accession and Version

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