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PKLR pyruvate kinase L/R [ Rana temporaria (common frog) ]

Gene ID: 120920890, updated on 21-Mar-2024

Summary

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Gene symbol
PKLR
Gene description
pyruvate kinase L/R
See related
EnsemblRapid:ENSRTEG00010002362
Gene type
protein coding
RefSeq status
MODEL
Organism
Rana temporaria
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana; Rana
Orthologs
human mouse all
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Genomic context

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See PKLR in Genome Data Viewer
Location:
chromosome: 13
Exon count:
12
Annotation release Status Assembly Chr Location
100 current aRanTem1.1 (GCF_905171775.1) 13 NC_053501.1 (120888190..120906511, complement)

Chromosome 13 - NC_053501.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120920562 Neighboring gene hyperpolarization activated cyclic nucleotide gated potassium channel 3 Neighboring gene farnesyl diphosphate synthase Neighboring gene extensin-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_053501.1 Chromosome 13 Reference aRanTem1.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables potassium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables pyruvate kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to insulin stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glycolytic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
pyruvate kinase PKLR

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Rana temporaria Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference aRanTem1.1

Genomic

  1. NC_053501.1 Reference aRanTem1.1

    Range
    120888190..120906511 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040333301.1 → XP_040189235.1  pyruvate kinase PKLR isoform X2

    Related
    ENSRTEP00010001725.1, ENSRTET00010003318.1
    Conserved Domains (1) summary
    cd00288
    Location:42 → 530
    Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...

  2. XM_040333302.1 → XP_040189236.1  pyruvate kinase PKLR isoform X2

    Related
    ENSRTEP00010001724.1, ENSRTET00010003317.1
    Conserved Domains (1) summary
    cd00288
    Location:42 → 530
    Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...

  3. XM_040333300.1 → XP_040189234.1  pyruvate kinase PKLR isoform X1

    Conserved Domains (1) summary
    cd00288
    Location:65 → 553
    Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...
Nucleotide Protein
Heading Accession and Version

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