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HSPG2 heparan sulfate proteoglycan 2 [ Rana temporaria (common frog) ]

Gene ID: 120916186, updated on 21-Mar-2024

Summary

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Gene symbol
HSPG2
Gene description
heparan sulfate proteoglycan 2
See related
EnsemblRapid:ENSRTEG00010016789
Gene type
protein coding
RefSeq status
MODEL
Organism
Rana temporaria
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Neobatrachia; Ranoidea; Ranidae; Rana; Rana
Orthologs
human mouse all
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Genomic context

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See HSPG2 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
97
Annotation release Status Assembly Chr Location
100 current aRanTem1.1 (GCF_905171775.1) 10 NC_053498.1 (1168645..1277824, complement)

Chromosome 10 - NC_053498.1Genomic Context describing neighboring genes Neighboring gene ubiquitin specific peptidase 48 Neighboring gene low density lipoprotein receptor class A domain containing 2 Neighboring gene uncharacterized LOC120916188 Neighboring gene transmembrane protein 269 Neighboring gene tyrosine-protein kinase STYK1-like Neighboring gene filamin binding LIM protein 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_053498.1 Chromosome 10 Reference aRanTem1.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables axon guidance receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in synapse organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cell-cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuronal cell body IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
basement membrane-specific heparan sulfate proteoglycan core protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Rana temporaria Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference aRanTem1.1

Genomic

  1. NC_053498.1 Reference aRanTem1.1

    Range
    1168645..1277824 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040327021.1 → XP_040182955.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X4

    Conserved Domains (12) summary
    cd05743
    Location:401 → 478
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
    smart00408
    Location:3399 → 3458
    IGc2; Immunoglobulin C-2 Type
    smart00180
    Location:1254 → 1299
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1572 → 1693
    LamB; Laminin B domain
    smart00409
    Location:1860 → 1940
    IG; Immunoglobulin
    smart00410
    Location:2069 → 2147
    IG_like; Immunoglobulin like
    cd00054
    Location:3952 → 3983
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1138 → 1187
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:4009 → 4167
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:265 → 299
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00096
    Location:2063 → 2069
    Ig; Ig strand A [structural motif]
    cl02507
    Location:15 → 125
    SEA; SEA domain

  2. XM_040327027.1 → XP_040182961.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X9

    Conserved Domains (12) summary
    cd05743
    Location:374 → 451
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
    smart00408
    Location:3372 → 3431
    IGc2; Immunoglobulin C-2 Type
    smart00180
    Location:1227 → 1272
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1545 → 1666
    LamB; Laminin B domain
    smart00409
    Location:2042 → 2120
    IG; Immunoglobulin
    smart00410
    Location:3278 → 3354
    IG_like; Immunoglobulin like
    cd00054
    Location:3925 → 3956
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1111 → 1160
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3982 → 4140
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:238 → 272
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00096
    Location:3278 → 3283
    Ig; Ig strand A' [structural motif]
    cl02507
    Location:15 → 126
    SEA; SEA domain

  3. XM_040327029.1 → XP_040182963.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X11

    Related
    ENSRTEP00010021461.1, ENSRTET00010028682.1
    Conserved Domains (12) summary
    cd05743
    Location:414 → 491
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
    smart00408
    Location:3212 → 3271
    IGc2; Immunoglobulin C-2 Type
    smart00180
    Location:1267 → 1312
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1383 → 1506
    LamB; Laminin B domain
    smart00409
    Location:2185 → 2262
    IG; Immunoglobulin
    smart00410
    Location:1882 → 1960
    IG_like; Immunoglobulin like
    cd00054
    Location:3765 → 3796
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1151 → 1200
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3822 → 3980
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:278 → 312
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00096
    Location:1893 → 1897
    Ig; Ig strand B [structural motif]
    cl02507
    Location:15 → 126
    SEA; SEA domain

  4. XM_040327023.1 → XP_040182957.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X6

    Conserved Domains (12) summary
    cd05743
    Location:414 → 491
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
    smart00408
    Location:3392 → 3451
    IGc2; Immunoglobulin C-2 Type
    smart00180
    Location:1267 → 1312
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1585 → 1706
    LamB; Laminin B domain
    smart00409
    Location:1873 → 1953
    IG; Immunoglobulin
    smart00410
    Location:2062 → 2140
    IG_like; Immunoglobulin like
    cd00054
    Location:3945 → 3976
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1151 → 1200
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:4002 → 4160
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:278 → 312
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00096
    Location:2056 → 2062
    Ig; Ig strand A [structural motif]
    cl02507
    Location:15 → 126
    SEA; SEA domain

  5. XM_040327026.1 → XP_040182960.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X8

    Conserved Domains (12) summary
    cd05743
    Location:414 → 491
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
    smart00408
    Location:3385 → 3444
    IGc2; Immunoglobulin C-2 Type
    smart00180
    Location:1267 → 1312
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1585 → 1706
    LamB; Laminin B domain
    smart00409
    Location:1969 → 2048
    IG; Immunoglobulin
    smart00410
    Location:2172 → 2252
    IG_like; Immunoglobulin like
    cd00054
    Location:3938 → 3969
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1151 → 1200
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3995 → 4153
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:278 → 312
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00096
    Location:2174 → 2178
    Ig; Ig strand A' [structural motif]
    cl02507
    Location:15 → 126
    SEA; SEA domain

  6. XM_040327019.1 → XP_040182953.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X2

    Conserved Domains (12) summary
    cd05743
    Location:414 → 491
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
    smart00408
    Location:3411 → 3470
    IGc2; Immunoglobulin C-2 Type
    smart00180
    Location:1267 → 1312
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1585 → 1706
    LamB; Laminin B domain
    smart00409
    Location:2082 → 2160
    IG; Immunoglobulin
    smart00410
    Location:3317 → 3393
    IG_like; Immunoglobulin like
    cd00054
    Location:3964 → 3995
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1151 → 1200
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:4021 → 4179
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:278 → 312
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00096
    Location:3317 → 3322
    Ig; Ig strand A' [structural motif]
    cl02507
    Location:15 → 126
    SEA; SEA domain

  7. XM_040327024.1 → XP_040182958.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X7

    Related
    ENSRTEP00010021422.1, ENSRTET00010028615.1
    Conserved Domains (12) summary
    cd05743
    Location:414 → 491
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
    smart00408
    Location:3386 → 3445
    IGc2; Immunoglobulin C-2 Type
    smart00180
    Location:1267 → 1312
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1585 → 1706
    LamB; Laminin B domain
    smart00409
    Location:1969 → 2048
    IG; Immunoglobulin
    smart00410
    Location:2173 → 2253
    IG_like; Immunoglobulin like
    cd00054
    Location:3939 → 3970
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1151 → 1200
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3996 → 4154
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:278 → 312
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00096
    Location:2184 → 2188
    Ig; Ig strand B [structural motif]
    cl02507
    Location:15 → 126
    SEA; SEA domain

  8. XM_040327028.1 → XP_040182962.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X10

    Conserved Domains (12) summary
    cd05743
    Location:414 → 491
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
    smart00408
    Location:3320 → 3379
    IGc2; Immunoglobulin C-2 Type
    smart00180
    Location:1267 → 1312
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1585 → 1706
    LamB; Laminin B domain
    smart00409
    Location:2173 → 2279
    IG; Immunoglobulin
    smart00410
    Location:2082 → 2160
    IG_like; Immunoglobulin like
    cd00054
    Location:3873 → 3904
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1151 → 1200
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3930 → 4088
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:278 → 312
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00096
    Location:2076 → 2082
    Ig; Ig strand A [structural motif]
    cl02507
    Location:15 → 126
    SEA; SEA domain

  9. XM_040327020.1 → XP_040182954.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X3

    Conserved Domains (12) summary
    cd05743
    Location:414 → 491
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
    smart00408
    Location:3412 → 3471
    IGc2; Immunoglobulin C-2 Type
    smart00180
    Location:1267 → 1312
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1585 → 1706
    LamB; Laminin B domain
    smart00409
    Location:2082 → 2160
    IG; Immunoglobulin
    smart00410
    Location:3318 → 3394
    IG_like; Immunoglobulin like
    cd00054
    Location:3959 → 3990
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1151 → 1200
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:4016 → 4174
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:278 → 312
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00096
    Location:3318 → 3323
    Ig; Ig strand A' [structural motif]
    cl02507
    Location:15 → 126
    SEA; SEA domain

  10. XM_040327022.1 → XP_040182956.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X5

    Conserved Domains (12) summary
    cd05743
    Location:414 → 491
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
    smart00408
    Location:3412 → 3471
    IGc2; Immunoglobulin C-2 Type
    smart00180
    Location:1267 → 1312
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1585 → 1706
    LamB; Laminin B domain
    smart00409
    Location:2082 → 2160
    IG; Immunoglobulin
    smart00410
    Location:3318 → 3394
    IG_like; Immunoglobulin like
    cd00054
    Location:3965 → 3996
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1151 → 1200
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:4004 → 4162
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:278 → 312
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00096
    Location:3318 → 3323
    Ig; Ig strand A' [structural motif]
    cl02507
    Location:15 → 126
    SEA; SEA domain

  11. XM_040327018.1 → XP_040182952.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X1

    Conserved Domains (12) summary
    cd05743
    Location:414 → 491
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
    smart00408
    Location:3412 → 3471
    IGc2; Immunoglobulin C-2 Type
    smart00180
    Location:1267 → 1312
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1585 → 1706
    LamB; Laminin B domain
    smart00409
    Location:2082 → 2160
    IG; Immunoglobulin
    smart00410
    Location:3318 → 3394
    IG_like; Immunoglobulin like
    cd00054
    Location:3965 → 3996
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1151 → 1200
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:4022 → 4180
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:278 → 312
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00096
    Location:3318 → 3323
    Ig; Ig strand A' [structural motif]
    cl02507
    Location:15 → 126
    SEA; SEA domain

  12. XM_040327030.1 → XP_040182964.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X12

    Related
    ENSRTEP00010021374.1, ENSRTET00010028533.1
    Conserved Domains (12) summary
    cd05743
    Location:401 → 478
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
    smart00408
    Location:3172 → 3231
    IGc2; Immunoglobulin C-2 Type
    smart00180
    Location:1254 → 1299
    EGF_Lam; Laminin-type epidermal growth factor-like domai
    smart00281
    Location:1370 → 1493
    LamB; Laminin B domain
    smart00409
    Location:2431 → 2509
    IG; Immunoglobulin
    smart00410
    Location:1959 → 2039
    IG_like; Immunoglobulin like
    cd00054
    Location:3719 → 3750
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1138 → 1187
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3776 → 3934
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:265 → 299
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd00096
    Location:1961 → 1965
    Ig; Ig strand A' [structural motif]
    cl02507
    Location:15 → 125
    SEA; SEA domain
Nucleotide Protein
Heading Accession and Version

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