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TJP2 tight junction protein 2 [ Hirundo rustica (Barn swallow) ]

Gene ID: 120765110, updated on 10-Oct-2024

Summary

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Gene symbol
TJP2
Gene description
tight junction protein 2
See related
EnsemblRapid:ENSHRRG00010010403
Gene type
protein coding
RefSeq status
MODEL
Organism
Hirundo rustica
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Passeriformes; Sylvioidea; Hirundinidae; Hirundo
Orthologs
human mouse all
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Genomic context

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See TJP2 in Genome Data Viewer
Location:
chromosome: Z
Exon count:
30
Annotation release Status Assembly Chr Location
RS_2023_07 current bHirRus1.pri.v3 (GCF_015227805.2) Z NC_053488.1 (35227496..35288107, complement)

Chromosome Z - NC_053488.1Genomic Context describing neighboring genes Neighboring gene 3-hydroxyacyl-CoA dehydratase 4 Neighboring gene interferon alpha-2-like Neighboring gene frataxin Neighboring gene phosphatidylinositol-4-phosphate 5-kinase type 1 beta

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_053488.1 Chromosome Z Reference bHirRus1.pri.v3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell junction organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment of endothelial intestinal barrier IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of blood-brain barrier permeability IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to cell-cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tight junction protein ZO-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_015227805.2-RS_2023_07

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bHirRus1.pri.v3

Genomic

  1. NC_053488.1 Reference bHirRus1.pri.v3

    Range
    35227496..35288107 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040089440.2 → XP_039945374.1  tight junction protein ZO-2 isoform X4

    UniProtKB/TrEMBL
    A0A7L4EXR8
    Conserved Domains (5) summary
    cd12027
    Location:573 → 635
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:669 → 848
    GuKc; Guanylate kinase homologues
    smart00228
    Location:273 → 351
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:162 → 254
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor

  2. XM_040089438.2 → XP_039945372.1  tight junction protein ZO-2 isoform X2

    UniProtKB/TrEMBL
    A0A7L4EXR8
    Conserved Domains (5) summary
    cd12027
    Location:597 → 659
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:693 → 872
    GuKc; Guanylate kinase homologues
    smart00228
    Location:297 → 375
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:33 → 118
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:186 → 278
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor

  3. XM_040089442.2 → XP_039945376.1  tight junction protein ZO-2 isoform X4

    UniProtKB/TrEMBL
    A0A7L4EXR8
    Conserved Domains (5) summary
    cd12027
    Location:573 → 635
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:669 → 848
    GuKc; Guanylate kinase homologues
    smart00228
    Location:273 → 351
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:162 → 254
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor

  4. XM_040089439.1 → XP_039945373.1  tight junction protein ZO-2 isoform X3

    UniProtKB/TrEMBL
    A0A7L4EXR8
    Conserved Domains (5) summary
    cd12027
    Location:584 → 646
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:680 → 859
    GuKc; Guanylate kinase homologues
    smart00228
    Location:284 → 362
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:20 → 105
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:173 → 265
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor

  5. XM_040089436.1 → XP_039945370.1  tight junction protein ZO-2 isoform X1

    UniProtKB/TrEMBL
    A0A7L4EXR8
    Conserved Domains (5) summary
    cd12027
    Location:628 → 690
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:724 → 903
    GuKc; Guanylate kinase homologues
    smart00228
    Location:328 → 406
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:64 → 149
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01642
    Location:217 → 309
    U2AF_lg; U2 snRNP auxilliary factor, large subunit, splicing factor

  6. XM_058424022.1 → XP_058280005.1  tight junction protein ZO-2 isoform X4

    Related
    ENSHRRP00010014193.2, ENSHRRT00010015065.2
Nucleotide Protein
Heading Accession and Version

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