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CBL Cbl proto-oncogene [ Hirundo rustica (Barn swallow) ]

Gene ID: 120762499, updated on 3-Aug-2024

Summary

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Gene symbol
CBL
Gene description
Cbl proto-oncogene
See related
EnsemblRapid:ENSHRRG00010011299
Gene type
protein coding
RefSeq status
MODEL
Organism
Hirundo rustica
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Passeriformes; Sylvioidea; Hirundinidae; Hirundo
Orthologs
human mouse all
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Genomic context

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See CBL in Genome Data Viewer
Location:
chromosome: 23
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2023_07 current bHirRus1.pri.v3 (GCF_015227805.2) 23 NC_053472.1 (5194561..5228738, complement)

Chromosome 23 - NC_053472.1Genomic Context describing neighboring genes Neighboring gene ring finger protein 26 Neighboring gene E3 ubiquitin-protein ligase RNF26-like Neighboring gene melanoma cell adhesion molecule Neighboring gene NHERF family PDZ scaffold protein 4 Neighboring gene NLR family member X1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_053472.1 Chromosome 23 Reference bHirRus1.pri.v3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables SH3 domain binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphotyrosine residue binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables receptor tyrosine kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of epidermal growth factor-activated receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane raft IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase CBL

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_015227805.2-RS_2023_07

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bHirRus1.pri.v3

Genomic

  1. NC_053472.1 Reference bHirRus1.pri.v3

    Range
    5194561..5228738 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040084965.2 → XP_039940899.1  E3 ubiquitin-protein ligase CBL

    UniProtKB/TrEMBL
    A0A7L4ERJ3
    Related
    ENSHRRP00010015237.1, ENSHRRT00010016172.2
    Conserved Domains (4) summary
    cd09920
    Location:240 → 336
    SH2_Cbl-b_TKB; Src homology 2 (SH2) domain found in the Cbl-b TKB domain
    PHA03247
    Location:464 → 707
    PHA03247; large tegument protein UL36; Provisional
    cd14393
    Location:854 → 893
    UBA_c-Cbl; UBA domain found in E3 ubiquitin-protein ligase Cbl and similar proteins
    cd16709
    Location:346 → 411
    RING-HC_Cbl-b; RING finger, HC subclass, found in E3 ubiquitin-protein ligase Cbl-b and similar proteins
Nucleotide Protein
Heading Accession and Version

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