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CRKL CRK like proto-oncogene, adaptor protein [ Hirundo rustica (Barn swallow) ]

Gene ID: 120760550, updated on 3-Aug-2024

Summary

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Gene symbol
CRKL
Gene description
CRK like proto-oncogene, adaptor protein
See related
EnsemblRapid:ENSHRRG00010004620
Gene type
protein coding
RefSeq status
MODEL
Organism
Hirundo rustica
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Passeriformes; Sylvioidea; Hirundinidae; Hirundo
Orthologs
human mouse all
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Genomic context

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See CRKL in Genome Data Viewer
Location:
chromosome: 17
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2023_07 current bHirRus1.pri.v3 (GCF_015227805.2) 17 NC_053466.1 (11605187..11622935)

Chromosome 17 - NC_053466.1Genomic Context describing neighboring genes Neighboring gene mediator complex subunit 15 Neighboring gene kelch like family member 22 Neighboring gene T-box-containing protein TBX6L Neighboring gene calcineurin binding protein 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_053466.1 Chromosome 17 Reference bHirRus1.pri.v3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of ERK1 and ERK2 cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
crk-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_015227805.2-RS_2023_07

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bHirRus1.pri.v3

Genomic

  1. NC_053466.1 Reference bHirRus1.pri.v3

    Range
    11605187..11622935
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040080966.2 → XP_039936900.1  crk-like protein isoform X1

    UniProtKB/TrEMBL
    A0A3M0JYK7
    Related
    ENSHRRP00010006437.1, ENSHRRT00010006803.2
    Conserved Domains (3) summary
    cd09926
    Location:7 → 107
    SH2_CRK_like; Src homology 2 domain found in cancer-related signaling adaptor protein CRK
    cd11758
    Location:128 → 181
    SH3_CRK_N; N-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins
    cd11759
    Location:237 → 293
    SH3_CRK_C; C-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins

  2. XM_040080967.2 → XP_039936901.1  crk-like protein isoform X2

    Conserved Domains (3) summary
    cd09926
    Location:7 → 107
    SH2_CRK_like; Src homology 2 domain found in cancer-related signaling adaptor protein CRK
    cd11758
    Location:128 → 181
    SH3_CRK_N; N-terminal Src Homology 3 domain of Ct10 Regulator of Kinase adaptor proteins
    cl17036
    Location:237 → 259
    SH3; Src Homology 3 domain superfamily
Nucleotide Protein
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