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traf2a Tnf receptor-associated factor 2a [ Polypterus senegalus (gray bichir) ]

Gene ID: 120543219, updated on 8-May-2024

Summary

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Gene symbol
traf2a
Gene description
Tnf receptor-associated factor 2a
Locus tag
GTO96_0006779
See related
EnsemblRapid:ENSSTSG00000022238
Gene type
protein coding
RefSeq status
MODEL
Organism
Polypterus senegalus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Polypteriformes; Polypteridae; Polypterus
Also known as
Traf2_1
Orthologs
zebrafish all
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Genomic context

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See traf2a in Genome Data Viewer
Location:
chromosome: 13
Exon count:
11
Annotation release Status Assembly Chr Location
100 current ASM1683550v1 (GCF_016835505.1) 13 NC_053166.1 (3062294..3083523, complement)

Chromosome 13 - NC_053166.1Genomic Context describing neighboring genes Neighboring gene PKc_LIMK_like_unk domain-containing protein Neighboring gene tenascin-like Neighboring gene NADPH dependent diflavin oxidoreductase 1 Neighboring gene FK506-binding protein 15-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_053166.1 Chromosome 13 Reference ASM1683550v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables tumor necrosis factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin-protein transferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of JNK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of NF-kappaB transcription factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein K63-linked ubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tumor necrosis factor-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasmic side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of plasma membrane signaling receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
TNF receptor-associated factor 2
Names
TRAF2 factor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Polypterus senegalus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1683550v1 Primary Assembly

Genomic

  1. NC_053166.1 Reference ASM1683550v1 Primary Assembly

    Range
    3062294..3083523 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039776161.1 → XP_039632095.1  TNF receptor-associated factor 2

    UniProtKB/TrEMBL
    A0A8X7WRC1
    Conserved Domains (6) summary
    COG4372
    Location:264 → 404
    COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]
    TIGR00599
    Location:34 → 157
    rad18; DNA repair protein rad18
    cd00162
    Location:34 → 72
    RING_Ubox; RING-HC finger (C3HC4-type) [structural motif]
    cl02446
    Location:390 → 553
    MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
    cl17238
    Location:32 → 73
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
    cl40617
    Location:178 → 235
    zf-TRAF; TRAF-type zinc finger

  2. XM_039776162.1 → XP_039632096.1  TNF receptor-associated factor 2

    UniProtKB/TrEMBL
    A0A8X7WRC1
    Related
    ENSSTSP00000051447.1, ENSSTST00000058247.1
    Conserved Domains (6) summary
    COG4372
    Location:264 → 404
    COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]
    TIGR00599
    Location:34 → 157
    rad18; DNA repair protein rad18
    cd00162
    Location:34 → 72
    RING_Ubox; RING-HC finger (C3HC4-type) [structural motif]
    cl02446
    Location:390 → 553
    MATH; MATH (meprin and TRAF-C homology) domain; an independent folding unit with an eight-stranded beta-sandwich structure found in meprins, TRAFs and other proteins. Meprins comprise a class of extracellular metalloproteases which are anchored to the membrane ...
    cl17238
    Location:32 → 73
    RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
    cl40617
    Location:178 → 235
    zf-TRAF; TRAF-type zinc finger
Nucleotide Protein
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