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cbl Cbl proto-oncogene, E3 ubiquitin protein ligase [ Polypterus senegalus (gray bichir) ]

Gene ID: 120535976, updated on 8-May-2024

Summary

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Gene symbol
cbl
Gene description
Cbl proto-oncogene, E3 ubiquitin protein ligase
Locus tag
GTO96_0023208
See related
EnsemblRapid:ENSSTSG00000022156
Gene type
protein coding
RefSeq status
MODEL
Organism
Polypterus senegalus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Polypteriformes; Polypteridae; Polypterus
Orthologs
human zebrafish all
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Genomic context

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See cbl in Genome Data Viewer
Location:
chromosome: 9
Exon count:
16
Annotation release Status Assembly Chr Location
100 current ASM1683550v1 (GCF_016835505.1) 9 NC_053162.1 (171156773..171254677, complement)

Chromosome 9 - NC_053162.1Genomic Context describing neighboring genes Neighboring gene ring finger protein 26 Neighboring gene cell surface glycoprotein MUC18-like Neighboring gene coxsackievirus and adenovirus receptor homolog Neighboring gene dynein regulatory complex subunit 12 homolog Neighboring gene uroplakin 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_053162.1 Chromosome 9 Reference ASM1683550v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables SH3 domain binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphotyrosine residue binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables receptor tyrosine kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of epidermal growth factor-activated receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane raft IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase CBL
Names
CBL ligase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Polypterus senegalus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1683550v1 Primary Assembly

Genomic

  1. NC_053162.1 Reference ASM1683550v1 Primary Assembly

    Range
    171156773..171254677 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039764228.1 → XP_039620162.1  E3 ubiquitin-protein ligase CBL

    UniProtKB/TrEMBL
    A0A8X7XIZ0
    Related
    ENSSTSP00000051352.1, ENSSTST00000058152.1
    Conserved Domains (4) summary
    cd09920
    Location:240 → 336
    SH2_Cbl-b_TKB; Src homology 2 (SH2) domain found in the Cbl-b TKB domain
    PHA03247
    Location:437 → 711
    PHA03247; large tegument protein UL36; Provisional
    cd14393
    Location:862 → 901
    UBA_c-Cbl; UBA domain found in E3 ubiquitin-protein ligase Cbl and similar proteins
    cd16709
    Location:346 → 411
    RING-HC_Cbl-b; RING finger, HC subclass, found in E3 ubiquitin-protein ligase Cbl-b and similar proteins
Nucleotide Protein
Heading Accession and Version

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