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TJP2 tight junction protein 2 [ Mauremys reevesii (Reeves's turtle) ]

Gene ID: 120407589, updated on 21-Mar-2024

Summary

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Gene symbol
TJP2
Gene description
tight junction protein 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Mauremys reevesii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira; Testudinoidea; Geoemydidae; Geoemydinae; Mauremys
Orthologs
human mouse all
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Genomic context

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See TJP2 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
32
Annotation release Status Assembly LG Location
100 current ASM1616193v1 (GCF_016161935.1) 6 NC_052628.1 (90478689..90562482)

Linkage Group 6 - NC_052628.1Genomic Context describing neighboring genes Neighboring gene phosphatidylinositol-4-phosphate 5-kinase type 1 beta Neighboring gene uncharacterized LOC120407592 Neighboring gene frataxin Neighboring gene uncharacterized LOC120407590 Neighboring gene endosomal transmembrane epsin interactor 1 Neighboring gene amyloid beta precursor protein binding family A member 1 Neighboring gene uncharacterized LOC120408699

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_052628.1 Chromosome 6 Reference ASM1616193v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell junction organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment of endothelial intestinal barrier IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of blood-brain barrier permeability IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to cell-cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tight junction protein ZO-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mauremys reevesii Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1616193v1 Primary Assembly

Genomic

  1. NC_052628.1 Reference ASM1616193v1 Primary Assembly

    Range
    90478689..90562482
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039543296.1 → XP_039399230.1  tight junction protein ZO-2 isoform X5

    Conserved Domains (4) summary
    cd12027
    Location:604 → 666
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:700 → 879
    GuKc; Guanylate kinase homologues
    smart00228
    Location:304 → 383
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:19 → 103
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  2. XM_039543293.1 → XP_039399227.1  tight junction protein ZO-2 isoform X5

    Conserved Domains (4) summary
    cd12027
    Location:604 → 666
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:700 → 879
    GuKc; Guanylate kinase homologues
    smart00228
    Location:304 → 383
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:19 → 103
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  3. XM_039543297.1 → XP_039399231.1  tight junction protein ZO-2 isoform X3

    Conserved Domains (4) summary
    cd12027
    Location:595 → 657
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:691 → 870
    GuKc; Guanylate kinase homologues
    smart00228
    Location:295 → 374
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  4. XM_039543299.1 → XP_039399233.1  tight junction protein ZO-2 isoform X3

    Conserved Domains (4) summary
    cd12027
    Location:595 → 657
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:691 → 870
    GuKc; Guanylate kinase homologues
    smart00228
    Location:295 → 374
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  5. XM_039543295.1 → XP_039399229.1  tight junction protein ZO-2 isoform X5

    Conserved Domains (4) summary
    cd12027
    Location:604 → 666
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:700 → 879
    GuKc; Guanylate kinase homologues
    smart00228
    Location:304 → 383
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:19 → 103
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  6. XM_039543303.1 → XP_039399237.1  tight junction protein ZO-2 isoform X5

    Conserved Domains (4) summary
    cd12027
    Location:604 → 666
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:700 → 879
    GuKc; Guanylate kinase homologues
    smart00228
    Location:304 → 383
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:19 → 103
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  7. XM_039543301.1 → XP_039399235.1  tight junction protein ZO-2 isoform X3

    Conserved Domains (4) summary
    cd12027
    Location:595 → 657
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:691 → 870
    GuKc; Guanylate kinase homologues
    smart00228
    Location:295 → 374
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  8. XM_039543302.1 → XP_039399236.1  tight junction protein ZO-2 isoform X5

    Conserved Domains (4) summary
    cd12027
    Location:604 → 666
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:700 → 879
    GuKc; Guanylate kinase homologues
    smart00228
    Location:304 → 383
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:19 → 103
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  9. XM_039543294.1 → XP_039399228.1  tight junction protein ZO-2 isoform X5

    Conserved Domains (4) summary
    cd12027
    Location:604 → 666
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:700 → 879
    GuKc; Guanylate kinase homologues
    smart00228
    Location:304 → 383
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:19 → 103
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  10. XM_039543291.1 → XP_039399225.1  tight junction protein ZO-2 isoform X3

    Conserved Domains (4) summary
    cd12027
    Location:595 → 657
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:691 → 870
    GuKc; Guanylate kinase homologues
    smart00228
    Location:295 → 374
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  11. XM_039543290.1 → XP_039399224.1  tight junction protein ZO-2 isoform X2

    Conserved Domains (4) summary
    cd12027
    Location:619 → 681
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:715 → 894
    GuKc; Guanylate kinase homologues
    smart00228
    Location:319 → 398
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:33 → 118
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  12. XM_039543292.1 → XP_039399226.1  tight junction protein ZO-2 isoform X4

    Conserved Domains (4) summary
    cd12027
    Location:615 → 677
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:711 → 890
    GuKc; Guanylate kinase homologues
    smart00228
    Location:315 → 394
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:30 → 114
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  13. XM_039543298.1 → XP_039399232.1  tight junction protein ZO-2 isoform X3

    Conserved Domains (4) summary
    cd12027
    Location:595 → 657
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:691 → 870
    GuKc; Guanylate kinase homologues
    smart00228
    Location:295 → 374
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

  14. XM_039543288.1 → XP_039399222.1  tight junction protein ZO-2 isoform X1

    Conserved Domains (4) summary
    cd12027
    Location:981 → 1043
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:1077 → 1256
    GuKc; Guanylate kinase homologues
    smart00228
    Location:681 → 760
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:395 → 480
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
Nucleotide Protein
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