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FGD4 FYVE, RhoGEF and PH domain containing 4 [ Mauremys reevesii (Reeves's turtle) ]

Gene ID: 120368623, updated on 21-Mar-2024

Summary

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Gene symbol
FGD4
Gene description
FYVE, RhoGEF and PH domain containing 4
Gene type
protein coding
RefSeq status
MODEL
Organism
Mauremys reevesii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira; Testudinoidea; Geoemydidae; Geoemydinae; Mauremys
Orthologs
human mouse all
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Genomic context

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See FGD4 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
22
Annotation release Status Assembly LG Location
100 current ASM1616193v1 (GCF_016161935.1) 1 NC_052623.1 (254329587..254534503)

Linkage Group 1 - NC_052623.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC120395990 Neighboring gene retroelement silencing factor 1 Neighboring gene BICD cargo adaptor 1 Neighboring gene uncharacterized LOC120368658 Neighboring gene dynamin 1 like Neighboring gene tyrosyl-tRNA synthetase 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_052623.1 Chromosome 1 Reference ASM1616193v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Using genes as characters and a parsimony analysis to explore the phylogenetic position of turtles. Lu B, et al. PLoS One, 2013. PMID 24278129, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in filopodium assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
FYVE, RhoGEF and PH domain-containing protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mauremys reevesii Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1616193v1 Primary Assembly

Genomic

  1. NC_052623.1 Reference ASM1616193v1 Primary Assembly

    Range
    254329587..254534503
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039480867.1 → XP_039336801.1  FYVE, RhoGEF and PH domain-containing protein 4 isoform X1

    Conserved Domains (4) summary
    cd00160
    Location:333 → 517
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd13236
    Location:764 → 866
    PH2_FGD1-4; FYVE, RhoGEF and PH domain containing/faciogenital dysplasia proteins pleckstrin homology (PH) domain, C-terminus
    cd15791
    Location:549 → 642
    PH1_FDG4; FYVE, RhoGEF and PH domain containing/faciogenital dysplasia proteins 4, N-terminal Pleckstrin homology (PH) domain
    cd15741
    Location:681 → 745
    FYVE_FGD1_2_4; FYVE domain found in FYVE, RhoGEF and PH domain-containing protein facio-genital dysplasia FGD1, FGD2, FGD4

  2. XM_039480897.1 → XP_039336831.1  FYVE, RhoGEF and PH domain-containing protein 4 isoform X4

    Conserved Domains (4) summary
    cd00160
    Location:290 → 474
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd13236
    Location:721 → 823
    PH2_FGD1-4; FYVE, RhoGEF and PH domain containing/faciogenital dysplasia proteins pleckstrin homology (PH) domain, C-terminus
    cd15791
    Location:506 → 599
    PH1_FDG4; FYVE, RhoGEF and PH domain containing/faciogenital dysplasia proteins 4, N-terminal Pleckstrin homology (PH) domain
    cd15741
    Location:638 → 702
    FYVE_FGD1_2_4; FYVE domain found in FYVE, RhoGEF and PH domain-containing protein facio-genital dysplasia FGD1, FGD2, FGD4

  3. XM_039480886.1 → XP_039336820.1  FYVE, RhoGEF and PH domain-containing protein 4 isoform X3

    Conserved Domains (4) summary
    cd00160
    Location:290 → 474
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd13236
    Location:721 → 823
    PH2_FGD1-4; FYVE, RhoGEF and PH domain containing/faciogenital dysplasia proteins pleckstrin homology (PH) domain, C-terminus
    cd15741
    Location:638 → 702
    FYVE_FGD1_2_4; FYVE domain found in FYVE, RhoGEF and PH domain-containing protein facio-genital dysplasia FGD1, FGD2, FGD4
    cl17171
    Location:506 → 599
    PH-like; Pleckstrin homology-like domain

  4. XM_039480876.1 → XP_039336810.1  FYVE, RhoGEF and PH domain-containing protein 4 isoform X2

    Conserved Domains (4) summary
    cd00160
    Location:290 → 474
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd13236
    Location:721 → 823
    PH2_FGD1-4; FYVE, RhoGEF and PH domain containing/faciogenital dysplasia proteins pleckstrin homology (PH) domain, C-terminus
    cd15741
    Location:638 → 702
    FYVE_FGD1_2_4; FYVE domain found in FYVE, RhoGEF and PH domain-containing protein facio-genital dysplasia FGD1, FGD2, FGD4
    cl17171
    Location:506 → 599
    PH-like; Pleckstrin homology-like domain

  5. XM_039480907.1 → XP_039336841.1  FYVE, RhoGEF and PH domain-containing protein 4 isoform X5

    Conserved Domains (4) summary
    cd00160
    Location:239 → 423
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd13236
    Location:670 → 772
    PH2_FGD1-4; FYVE, RhoGEF and PH domain containing/faciogenital dysplasia proteins pleckstrin homology (PH) domain, C-terminus
    cd15741
    Location:587 → 651
    FYVE_FGD1_2_4; FYVE domain found in FYVE, RhoGEF and PH domain-containing protein facio-genital dysplasia FGD1, FGD2, FGD4
    cl17171
    Location:455 → 548
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
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