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SPTBN2 spectrin beta, non-erythrocytic 2 [ Crotalus tigris (Tiger rattlesnake) ]

Gene ID: 120318527, updated on 21-Mar-2024

Summary

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Gene symbol
SPTBN2
Gene description
spectrin beta, non-erythrocytic 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Crotalus tigris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Serpentes; Colubroidea; Viperidae; Crotalinae; Crotalus
Orthologs
human mouse all
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Genomic context

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See SPTBN2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
40
Annotation release Status Assembly Chr Location
100 current ASM1654583v1 (GCF_016545835.1) Unplaced Scaffold NW_024097926.1 (871774..953745, complement)

NW_024097926.1Genomic Context describing neighboring genes Neighboring gene RNA-binding protein 4B-like Neighboring gene copper chaperone for superoxide dismutase Neighboring gene coiled-coil domain containing 87 Neighboring gene acylphosphatase-2-like Neighboring gene TOP6B like initiator of meiotic double strand breaks Neighboring gene Ras converting CAAX endopeptidase 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_024097926 Unplaced Scaffold Reference ASM1654583v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phospholipid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables structural constituent of cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cortical actin cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of spectrin IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
spectrin beta chain, non-erythrocytic 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Crotalus tigris Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1654583v1

Genomic

  1. NW_024097926.1 Reference ASM1654583v1

    Range
    871774..953745 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039366239.1 → XP_039222173.1  spectrin beta chain, non-erythrocytic 2 isoform X1

    Conserved Domains (6) summary
    smart00150
    Location:2022 → 2098
    SPEC; Spectrin repeats
    cd00176
    Location:645 → 852
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd10571
    Location:2216 → 2319
    PH_beta_spectrin; Beta-spectrin pleckstrin homology (PH) domain
    pfam00435
    Location:429 → 528
    Spectrin; Spectrin repeat
    cd21317
    Location:29 → 159
    CH_SPTBN2_rpt1; first calponin homology (CH) domain found in spectrin beta chain, non-erythrocytic 2 (SPTBN2) and similar proteins
    cd21321
    Location:173 → 291
    CH_SPTBN2_rpt2; second calponin homology (CH) domain found in spectrin beta chain, non-erythrocytic 2 (SPTBN2) and similar proteins

  2. XM_039366237.1 → XP_039222171.1  spectrin beta chain, non-erythrocytic 2 isoform X1

    Conserved Domains (6) summary
    smart00150
    Location:2022 → 2098
    SPEC; Spectrin repeats
    cd00176
    Location:645 → 852
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd10571
    Location:2216 → 2319
    PH_beta_spectrin; Beta-spectrin pleckstrin homology (PH) domain
    pfam00435
    Location:429 → 528
    Spectrin; Spectrin repeat
    cd21317
    Location:29 → 159
    CH_SPTBN2_rpt1; first calponin homology (CH) domain found in spectrin beta chain, non-erythrocytic 2 (SPTBN2) and similar proteins
    cd21321
    Location:173 → 291
    CH_SPTBN2_rpt2; second calponin homology (CH) domain found in spectrin beta chain, non-erythrocytic 2 (SPTBN2) and similar proteins

  3. XM_039366238.1 → XP_039222172.1  spectrin beta chain, non-erythrocytic 2 isoform X1

    Conserved Domains (6) summary
    smart00150
    Location:2022 → 2098
    SPEC; Spectrin repeats
    cd00176
    Location:645 → 852
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd10571
    Location:2216 → 2319
    PH_beta_spectrin; Beta-spectrin pleckstrin homology (PH) domain
    pfam00435
    Location:429 → 528
    Spectrin; Spectrin repeat
    cd21317
    Location:29 → 159
    CH_SPTBN2_rpt1; first calponin homology (CH) domain found in spectrin beta chain, non-erythrocytic 2 (SPTBN2) and similar proteins
    cd21321
    Location:173 → 291
    CH_SPTBN2_rpt2; second calponin homology (CH) domain found in spectrin beta chain, non-erythrocytic 2 (SPTBN2) and similar proteins

  4. XM_039366240.1 → XP_039222174.1  spectrin beta chain, non-erythrocytic 2 isoform X1

    Conserved Domains (6) summary
    smart00150
    Location:2022 → 2098
    SPEC; Spectrin repeats
    cd00176
    Location:645 → 852
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd10571
    Location:2216 → 2319
    PH_beta_spectrin; Beta-spectrin pleckstrin homology (PH) domain
    pfam00435
    Location:429 → 528
    Spectrin; Spectrin repeat
    cd21317
    Location:29 → 159
    CH_SPTBN2_rpt1; first calponin homology (CH) domain found in spectrin beta chain, non-erythrocytic 2 (SPTBN2) and similar proteins
    cd21321
    Location:173 → 291
    CH_SPTBN2_rpt2; second calponin homology (CH) domain found in spectrin beta chain, non-erythrocytic 2 (SPTBN2) and similar proteins

  5. XM_039366242.1 → XP_039222176.1  spectrin beta chain, non-erythrocytic 2 isoform X2

    Conserved Domains (6) summary
    smart00150
    Location:2014 → 2090
    SPEC; Spectrin repeats
    cd00176
    Location:637 → 844
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd10571
    Location:2208 → 2311
    PH_beta_spectrin; Beta-spectrin pleckstrin homology (PH) domain
    pfam00435
    Location:421 → 520
    Spectrin; Spectrin repeat
    cd21246
    Location:37 → 151
    CH_SPTB-like_rpt1; first calponin homology (CH) domain found in the beta-I spectrin-like subfamily
    cd21321
    Location:165 → 283
    CH_SPTBN2_rpt2; second calponin homology (CH) domain found in spectrin beta chain, non-erythrocytic 2 (SPTBN2) and similar proteins
Nucleotide Protein
Heading Accession and Version

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