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FBN1 fibrillin 1 [ Crotalus tigris (Tiger rattlesnake) ]

Gene ID: 120315152, updated on 21-Mar-2024

Summary

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Gene symbol
FBN1
Gene description
fibrillin 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Crotalus tigris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Serpentes; Colubroidea; Viperidae; Crotalinae; Crotalus
Orthologs
human mouse all
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Genomic context

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See FBN1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
67
Annotation release Status Assembly Chr Location
100 current ASM1654583v1 (GCF_016545835.1) Unplaced Scaffold NW_024097358.1 (5461664..5623752)

NW_024097358.1Genomic Context describing neighboring genes Neighboring gene SHC adaptor protein 4 Neighboring gene centrosomal protein 152 Neighboring gene zinc finger BED domain-containing protein 5-like Neighboring gene solute carrier family 12 member 1 Neighboring gene deoxyuridine triphosphatase

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_024097358 Unplaced Scaffold Reference ASM1654583v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
fibrillin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Crotalus tigris Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1654583v1

Genomic

  1. NW_024097358.1 Reference ASM1654583v1

    Range
    5461664..5623752
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039359016.1 → XP_039214950.1  fibrillin-1 isoform X1

    Conserved Domains (10) summary
    smart00179
    Location:1828 → 1860
    EGF_CA; Calcium-binding EGF-like domain
    cd00054
    Location:785 → 819
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam07645
    Location:1950 → 1991
    EGF_CA; Calcium-binding EGF domain
    pfam00683
    Location:1569 → 1610
    TB; TB domain
    pfam12662
    Location:2486 → 2509
    cEGF; Complement Clr-like EGF-like
    pfam12947
    Location:1387 → 1422
    EGF_3; EGF domain
    pfam14670
    Location:1221 → 1256
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    pfam18193
    Location:74 → 107
    Fibrillin_U_N; Fibrillin 1 unique N-terminal domain
    cl00057
    Location:2460 → 2503
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    cl21504
    Location:313 → 353
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

  2. XM_039359017.1 → XP_039214951.1  fibrillin-1 isoform X2

    Conserved Domains (10) summary
    smart00179
    Location:1828 → 1860
    EGF_CA; Calcium-binding EGF-like domain
    cd00054
    Location:785 → 819
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam07645
    Location:1950 → 1991
    EGF_CA; Calcium-binding EGF domain
    pfam00683
    Location:1569 → 1610
    TB; TB domain
    pfam12662
    Location:1070 → 1093
    cEGF; Complement Clr-like EGF-like
    pfam12947
    Location:1387 → 1422
    EGF_3; EGF domain
    pfam14670
    Location:1221 → 1256
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    pfam18193
    Location:74 → 107
    Fibrillin_U_N; Fibrillin 1 unique N-terminal domain
    cl00057
    Location:2225 → 2264
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    cl21504
    Location:313 → 353
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

  3. XM_039359018.1 → XP_039214952.1  fibrillin-1 isoform X2

    Conserved Domains (10) summary
    smart00179
    Location:1828 → 1860
    EGF_CA; Calcium-binding EGF-like domain
    cd00054
    Location:785 → 819
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam07645
    Location:1950 → 1991
    EGF_CA; Calcium-binding EGF domain
    pfam00683
    Location:1569 → 1610
    TB; TB domain
    pfam12662
    Location:1070 → 1093
    cEGF; Complement Clr-like EGF-like
    pfam12947
    Location:1387 → 1422
    EGF_3; EGF domain
    pfam14670
    Location:1221 → 1256
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    pfam18193
    Location:74 → 107
    Fibrillin_U_N; Fibrillin 1 unique N-terminal domain
    cl00057
    Location:2225 → 2264
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    cl21504
    Location:313 → 353
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
Nucleotide Protein
Heading Accession and Version

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