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CBLC Cbl proto-oncogene C [ Crotalus tigris (Tiger rattlesnake) ]

Gene ID: 120312027, updated on 21-Mar-2024

Summary

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Gene symbol
CBLC
Gene description
Cbl proto-oncogene C
Gene type
protein coding
RefSeq status
MODEL
Organism
Crotalus tigris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Serpentes; Colubroidea; Viperidae; Crotalinae; Crotalus
Orthologs
human mouse all
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Genomic context

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See CBLC in Genome Data Viewer
Location:
chromosome: Un
Exon count:
11
Annotation release Status Assembly Chr Location
100 current ASM1654583v1 (GCF_016545835.1) Unplaced Scaffold NW_024096990.1 (1692534..1709983)

NW_024096990.1Genomic Context describing neighboring genes Neighboring gene carcinoembryonic antigen-related cell adhesion molecule 8-like Neighboring gene BCL3 transcription coactivator Neighboring gene basal cell adhesion molecule (Lutheran blood group) Neighboring gene nectin cell adhesion molecule 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_024096990 Unplaced Scaffold Reference ASM1654583v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables SH3 domain binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphotyrosine residue binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables receptor tyrosine kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of epidermal growth factor-activated receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane raft IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase CBL-C

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Crotalus tigris Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1654583v1

Genomic

  1. NW_024096990.1 Reference ASM1654583v1

    Range
    1692534..1709983
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039352227.1 → XP_039208161.1  E3 ubiquitin-protein ligase CBL-C isoform X2

    Conserved Domains (5) summary
    cd09920
    Location:222 → 315
    SH2_Cbl-b_TKB; Src homology 2 (SH2) domain found in the Cbl-b TKB domain
    COG5243
    Location:339 → 444
    HRD1; HRD ubiquitin ligase complex, ER membrane component [Posttranslational modification, protein turnover, chaperones]
    cd16502
    Location:344 → 386
    RING-HC_Cbl_like; RING finger, HC subclass, found in Casitas B-lineage lymphoma (Cbl) proteins
    pfam02262
    Location:18 → 137
    Cbl_N; CBL proto-oncogene N-terminal domain 1
    pfam02761
    Location:145 → 228
    Cbl_N2; CBL proto-oncogene N-terminus, EF hand-like domain

  2. XM_039352226.1 → XP_039208160.1  E3 ubiquitin-protein ligase CBL-C isoform X1

    Conserved Domains (5) summary
    cd09920
    Location:222 → 315
    SH2_Cbl-b_TKB; Src homology 2 (SH2) domain found in the Cbl-b TKB domain
    COG5243
    Location:339 → 456
    HRD1; HRD ubiquitin ligase complex, ER membrane component [Posttranslational modification, protein turnover, chaperones]
    cd16502
    Location:344 → 386
    RING-HC_Cbl_like; RING finger, HC subclass, found in Casitas B-lineage lymphoma (Cbl) proteins
    pfam02262
    Location:18 → 137
    Cbl_N; CBL proto-oncogene N-terminal domain 1
    pfam02761
    Location:145 → 228
    Cbl_N2; CBL proto-oncogene N-terminus, EF hand-like domain
Nucleotide Protein
Heading Accession and Version

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