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THBS1 thrombospondin 1 [ Crotalus tigris (Tiger rattlesnake) ]

Gene ID: 120307674, updated on 21-Mar-2024

Summary

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Gene symbol
THBS1
Gene description
thrombospondin 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Crotalus tigris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Serpentes; Colubroidea; Viperidae; Crotalinae; Crotalus
Orthologs
human mouse all
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Genomic context

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See THBS1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
22
Annotation release Status Assembly Chr Location
100 current ASM1654583v1 (GCF_016545835.1) Unplaced Scaffold NW_024096645.1 (2226169..2247477, complement)

NW_024096645.1Genomic Context describing neighboring genes Neighboring gene G protein-coupled receptor 176 Neighboring gene fibrous sheath interacting protein 1 Neighboring gene uncharacterized LOC120307637

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_024096645 Unplaced Scaffold Reference ASM1654583v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of angiogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
thrombospondin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Crotalus tigris Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1654583v1

Genomic

  1. NW_024096645.1 Reference ASM1654583v1

    Range
    2226169..2247477 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039342667.1 → XP_039198601.1  thrombospondin-1

    Conserved Domains (9) summary
    smart00209
    Location:435 → 487
    TSP1; Thrombospondin type 1 repeats
    sd00001
    Location:842 → 879
    TSP3; TSP3 repeat_long [structural motif]
    sd00002
    Location:784 → 818
    TSP3; TSP3 repeat_long [structural motif]
    sd00003
    Location:688 → 723
    TSP3_1C; TSP3 repeat_1C [structural motif]
    pfam00093
    Location:315 → 369
    VWC; von Willebrand factor type C domain
    pfam02412
    Location:843 → 879
    TSP_3; Thrombospondin type 3 repeat
    pfam05735
    Location:969 → 1166
    TSP_C; Thrombospondin C-terminal region
    pfam12947
    Location:647 → 686
    EGF_3; EGF domain
    cl22861
    Location:26 → 226
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
Nucleotide Protein
Heading Accession and Version

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