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HMGCL 3-hydroxy-3-methylglutaryl-CoA lyase [ Hyaena hyaena (striped hyena) ]

Gene ID: 120231310, updated on 11-Apr-2024

Summary

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Gene symbol
HMGCL
Gene description
3-hydroxy-3-methylglutaryl-CoA lyase
Gene type
protein coding
RefSeq status
MODEL
Organism
Hyaena hyaena
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Hyaenidae; Hyaena
Orthologs
human mouse all
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Genomic context

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See HMGCL in Genome Data Viewer
Location:
chromosome: Un
Exon count:
9
Annotation release Status Assembly Chr Location
100 current ASM300989v1 (GCF_003009895.1) Unplaced Scaffold NW_024080635.1 (8697070..8712758)

NW_024080635.1Genomic Context describing neighboring genes Neighboring gene cannabinoid receptor 2 Neighboring gene alpha-L-fucosidase 1 Neighboring gene UDP-galactose-4-epimerase Neighboring gene lysophospholipase 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_024080635 Unplaced Scaffold Reference ASM300989v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxymethylglutaryl-CoA lyase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in L-leucine catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ketone body biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hydroxymethylglutaryl-CoA lyase, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Hyaena hyaena Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM300989v1 Primary Assembly

Genomic

  1. NW_024080635.1 Reference ASM300989v1 Primary Assembly

    Range
    8697070..8712758
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039231375.1 → XP_039087306.1  hydroxymethylglutaryl-CoA lyase, mitochondrial isoform X1

    Conserved Domains (1) summary
    cd07938
    Location:35 → 308
    DRE_TIM_HMGL; 3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM barrel domain

  2. XM_039231383.1 → XP_039087314.1  hydroxymethylglutaryl-CoA lyase, mitochondrial isoform X2

    Conserved Domains (1) summary
    cl21457
    Location:29 → 289
    TIM; TIM-like beta/alpha barrel domains
Nucleotide Protein
Heading Accession and Version

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