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ect2 epithelial cell transforming 2 [ Micropterus salmoides (largemouth bass) ]

Gene ID: 119901253, updated on 21-Mar-2024

Summary

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Gene symbol
ect2
Gene description
epithelial cell transforming 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Micropterus salmoides
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Eupercaria; Centrarchiformes; Centrarchoidei; Centrarchidae; Micropterus
Orthologs
human zebrafish all
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Genomic context

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See ect2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
27
Annotation release Status Assembly Chr Location
100 current ASM1485139v1 (GCF_014851395.1) Unplaced Scaffold NW_024040374.1 (31262293..31317521, complement)

NW_024040374.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119901375 Neighboring gene uncharacterized LOC119901412 Neighboring gene MCF.2 cell line derived transforming sequence-like 2 Neighboring gene lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase A-like Neighboring gene replication factor C (activator 1) 4

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_024040374 Unplaced Scaffold Reference ASM1485139v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Discovery and validation of gene-linked diagnostic SNP markers for assessing hybridization between Largemouth bass (Micropterus salmoides) and Florida bass (M. floridanus). Li C, et al. Mol Ecol Resour, 2015 Mar. PMID 25047482
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in activation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitotic cytokinesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cytokinesis, actomyosin contractile ring assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell cortex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein ECT2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Micropterus salmoides Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1485139v1 Primary Assembly

Genomic

  1. NW_024040374.1 Reference ASM1485139v1 Primary Assembly

    Range
    31262293..31317521 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038716840.1 → XP_038572768.1  protein ECT2 isoform X5

    Conserved Domains (4) summary
    smart00325
    Location:518 → 700
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd01229
    Location:691 → 864
    PH_Ect2; Epithelial cell transforming 2 (Ect2) pleckstrin homology (PH) domain
    cd17732
    Location:271 → 350
    BRCT_Ect2_rpt2; second BRCT domain of epithelial cell-transforming sequence 2 protein (ECT2) and similar proteins
    cd17733
    Location:177 → 252
    BRCT_Ect2_rpt1; first BRCT domain of epithelial cell-transforming sequence 2 protein (ECT2) and similar proteins

  2. XM_038716841.1 → XP_038572769.1  protein ECT2 isoform X6

    Conserved Domains (4) summary
    smart00325
    Location:425 → 607
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    cd01229
    Location:598 → 771
    PH_Ect2; Epithelial cell transforming 2 (Ect2) pleckstrin homology (PH) domain
    cd17732
    Location:240 → 319
    BRCT_Ect2_rpt2; second BRCT domain of epithelial cell-transforming sequence 2 protein (ECT2) and similar proteins
    cd17733
    Location:146 → 221
    BRCT_Ect2_rpt1; first BRCT domain of epithelial cell-transforming sequence 2 protein (ECT2) and similar proteins

  3. XM_038716837.1 → XP_038572765.1  protein ECT2 isoform X2

    Conserved Domains (5) summary
    smart00325
    Location:487 → 669
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    COG5068
    Location:799 → 1064
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd01229
    Location:660 → 833
    PH_Ect2; Epithelial cell transforming 2 (Ect2) pleckstrin homology (PH) domain
    cd17732
    Location:240 → 319
    BRCT_Ect2_rpt2; second BRCT domain of epithelial cell-transforming sequence 2 protein (ECT2) and similar proteins
    cd17733
    Location:146 → 221
    BRCT_Ect2_rpt1; first BRCT domain of epithelial cell-transforming sequence 2 protein (ECT2) and similar proteins

  4. XM_038716835.1 → XP_038572763.1  protein ECT2 isoform X1

    Conserved Domains (5) summary
    smart00325
    Location:518 → 700
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    COG5068
    Location:830 → 1095
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd01229
    Location:691 → 864
    PH_Ect2; Epithelial cell transforming 2 (Ect2) pleckstrin homology (PH) domain
    cd17732
    Location:271 → 350
    BRCT_Ect2_rpt2; second BRCT domain of epithelial cell-transforming sequence 2 protein (ECT2) and similar proteins
    cd17733
    Location:177 → 252
    BRCT_Ect2_rpt1; first BRCT domain of epithelial cell-transforming sequence 2 protein (ECT2) and similar proteins

  5. XM_038716839.1 → XP_038572767.1  protein ECT2 isoform X4

    Conserved Domains (5) summary
    smart00325
    Location:425 → 607
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    COG5068
    Location:737 → 1002
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd01229
    Location:598 → 771
    PH_Ect2; Epithelial cell transforming 2 (Ect2) pleckstrin homology (PH) domain
    cd17732
    Location:240 → 319
    BRCT_Ect2_rpt2; second BRCT domain of epithelial cell-transforming sequence 2 protein (ECT2) and similar proteins
    cd17733
    Location:146 → 221
    BRCT_Ect2_rpt1; first BRCT domain of epithelial cell-transforming sequence 2 protein (ECT2) and similar proteins

  6. XM_038716838.1 → XP_038572766.1  protein ECT2 isoform X3

    Conserved Domains (5) summary
    smart00325
    Location:456 → 638
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
    COG5068
    Location:768 → 1033
    ARG80; Regulator of arginine metabolism and related MADS box-containing transcription factors [Transcription]
    cd01229
    Location:629 → 802
    PH_Ect2; Epithelial cell transforming 2 (Ect2) pleckstrin homology (PH) domain
    cd17732
    Location:271 → 350
    BRCT_Ect2_rpt2; second BRCT domain of epithelial cell-transforming sequence 2 protein (ECT2) and similar proteins
    cd17733
    Location:177 → 252
    BRCT_Ect2_rpt1; first BRCT domain of epithelial cell-transforming sequence 2 protein (ECT2) and similar proteins

RNA

  1. XR_005444153.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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