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MCM7 minichromosome maintenance complex component 7 [ Canis lupus familiaris (dog) ]

Gene ID: 119872149, updated on 17-Aug-2024

Summary

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Official Symbol
MCM7provided by VGNC
Official Full Name
minichromosome maintenance complex component 7provided by VGNC
Primary source
VGNC:VGNC:43087
See related
Ensembl:ENSCAFG00845002696
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See MCM7 in Genome Data Viewer
Location:
chromosome: 6
Exon count:
18
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 6 NC_051810.1 (9429534..9436847)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 6 NC_049227.1 (9438765..9446084)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 6 NC_049266.1 (9278839..9286173)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 6 NC_049747.1 (9259163..9266473)

Chromosome 6 - NC_051810.1Genomic Context describing neighboring genes Neighboring gene metallo-beta-lactamase domain containing 1 Neighboring gene canopy FGF signaling regulator 4 Neighboring gene TATA-box binding protein associated factor 6 Neighboring gene adaptor related protein complex 4 subunit mu 1 Neighboring gene microRNA mir-106b Neighboring gene microRNA mir-93 Neighboring gene microRNA mir-25 Neighboring gene COP9 signalosome subunit 6 Neighboring gene zinc finger and SCAN domain-containing protein 21-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Evaluation of minichromosome maintenance protein 7 as a prognostic marker in canine cutaneous mast cell tumours. Berlato D, et al. Vet Comp Oncol, 2012 Jun. PMID 22235877
  2. Ki-67 and minichromosome maintenance-7 (MCM7) expression in canine pituitary corticotroph adenomas. Ishino H, et al. Domest Anim Endocrinol, 2011 Nov. PMID 21982272

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. MCM7 was significantly associated with survival after controlling for age, surgical margins and histological grade.
    Title: Evaluation of minichromosome maintenance protein 7 as a prognostic marker in canine cutaneous mast cell tumours.
  2. MCM7 expression was significantly greater than Ki-67 expression in canine pituitary corticotroph adenomas.
    Title: Ki-67 and minichromosome maintenance-7 (MCM7) expression in canine pituitary corticotroph adenomas.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP hydrolysis activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-stranded DNA helicase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in DNA replication initiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in DNA strand elongation involved in DNA replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in DNA unwinding involved in DNA replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in double-strand break repair via break-induced replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of MCM complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA replication licensing factor MCM7

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051810.1 Reference ROS_Cfam_1.0

    Range
    9429534..9436847
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038668108.1 → XP_038524036.1  DNA replication licensing factor MCM7 isoform X1

    UniProtKB/TrEMBL
    A0A8C0SW35, A0A8C0T0J3, A0A8I3MQG2
    Related
    ENSCAFP00845003846.1, ENSCAFT00845004806.1
    Conserved Domains (2) summary
    smart00350
    Location:145 → 641
    MCM; minichromosome maintenance proteins
    pfam14551
    Location:10 → 93
    MCM_N; MCM N-terminal domain

  2. XM_038668109.1 → XP_038524037.1  DNA replication licensing factor MCM7 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KMP1, A0A8I3MK01
    Conserved Domains (2) summary
    smart00350
    Location:98 → 594
    MCM; minichromosome maintenance proteins
    pfam14551
    Location:2 → 46
    MCM_N; MCM N-terminal domain

  3. XM_038668111.1 → XP_038524039.1  DNA replication licensing factor MCM7 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KMP1, A0A8I3MK01
    Conserved Domains (2) summary
    smart00350
    Location:98 → 594
    MCM; minichromosome maintenance proteins
    pfam14551
    Location:2 → 46
    MCM_N; MCM N-terminal domain

  4. XM_038668110.1 → XP_038524038.1  DNA replication licensing factor MCM7 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KMP1, A0A8I3MK01
    Related
    ENSCAFP00845003888.1, ENSCAFT00845004859.1
    Conserved Domains (2) summary
    smart00350
    Location:98 → 594
    MCM; minichromosome maintenance proteins
    pfam14551
    Location:2 → 46
    MCM_N; MCM N-terminal domain

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049266.1 Alternate UMICH_Zoey_3.1

    Range
    9278839..9286173
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038478038.1 → XP_038333966.1  DNA replication licensing factor MCM7 isoform X1

    Conserved Domains (2) summary
    smart00350
    Location:145 → 641
    MCM; minichromosome maintenance proteins
    pfam14551
    Location:10 → 93
    MCM_N; MCM N-terminal domain

  2. XM_038478039.1 → XP_038333967.1  DNA replication licensing factor MCM7 isoform X2

    Conserved Domains (2) summary
    smart00350
    Location:98 → 594
    MCM; minichromosome maintenance proteins
    pfam14551
    Location:2 → 46
    MCM_N; MCM N-terminal domain

  3. XM_038478042.1 → XP_038333970.1  DNA replication licensing factor MCM7 isoform X2

    Conserved Domains (2) summary
    smart00350
    Location:98 → 594
    MCM; minichromosome maintenance proteins
    pfam14551
    Location:2 → 46
    MCM_N; MCM N-terminal domain

  4. XM_038478041.1 → XP_038333969.1  DNA replication licensing factor MCM7 isoform X2

    Conserved Domains (2) summary
    smart00350
    Location:98 → 594
    MCM; minichromosome maintenance proteins
    pfam14551
    Location:2 → 46
    MCM_N; MCM N-terminal domain

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049747.1 Alternate UNSW_CanFamBas_1.0

    Range
    9259163..9266473
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038603405.1 → XP_038459333.1  DNA replication licensing factor MCM7 isoform X1

  2. XM_038603406.1 → XP_038459334.1  DNA replication licensing factor MCM7 isoform X2

    Conserved Domains (2) summary
    smart00350
    Location:98 → 594
    MCM; minichromosome maintenance proteins
    pfam14551
    Location:2 → 46
    MCM_N; MCM N-terminal domain

  3. XM_038603408.1 → XP_038459336.1  DNA replication licensing factor MCM7 isoform X2

    Conserved Domains (2) summary
    smart00350
    Location:98 → 594
    MCM; minichromosome maintenance proteins
    pfam14551
    Location:2 → 46
    MCM_N; MCM N-terminal domain

  4. XM_038603407.1 → XP_038459335.1  DNA replication licensing factor MCM7 isoform X2

    Conserved Domains (2) summary
    smart00350
    Location:98 → 594
    MCM; minichromosome maintenance proteins
    pfam14551
    Location:2 → 46
    MCM_N; MCM N-terminal domain

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049227.1 Alternate UU_Cfam_GSD_1.0

    Range
    9438765..9446084
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038539315.1 → XP_038395243.1  DNA replication licensing factor MCM7 isoform X1

    UniProtKB/TrEMBL
    A0A8C0NTP3, A0A8C0T0J3

  2. XM_038539316.1 → XP_038395244.1  DNA replication licensing factor MCM7 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KMP1, A0A8I3MK01
    Conserved Domains (2) summary
    smart00350
    Location:98 → 594
    MCM; minichromosome maintenance proteins
    pfam14551
    Location:2 → 46
    MCM_N; MCM N-terminal domain

  3. XM_038539319.1 → XP_038395247.1  DNA replication licensing factor MCM7 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KMP1, A0A8I3MK01
    Conserved Domains (2) summary
    smart00350
    Location:98 → 594
    MCM; minichromosome maintenance proteins
    pfam14551
    Location:2 → 46
    MCM_N; MCM N-terminal domain

  4. XM_038539317.1 → XP_038395245.1  DNA replication licensing factor MCM7 isoform X2

    UniProtKB/TrEMBL
    A0A8C0KMP1, A0A8I3MK01
    Conserved Domains (2) summary
    smart00350
    Location:98 → 594
    MCM; minichromosome maintenance proteins
    pfam14551
    Location:2 → 46
    MCM_N; MCM N-terminal domain
Nucleotide Protein
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