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DTYMK deoxythymidylate kinase [ Canis lupus familiaris (dog) ]

Gene ID: 119865989, updated on 17-Aug-2024

Summary

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Official Symbol
DTYMKprovided by VGNC
Official Full Name
deoxythymidylate kinaseprovided by VGNC
Primary source
VGNC:VGNC:59076
Gene type
protein coding
RefSeq status
MODEL
Organism
Canis lupus familiaris (sub-species: familiaris)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs
human mouse all
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Genomic context

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See DTYMK in Genome Data Viewer
Location:
chromosome: 25
Exon count:
5
Annotation release Status Assembly Chr Location
106 current ROS_Cfam_1.0 (GCF_014441545.1) 25 NC_051829.1 (51718398..51728728, complement)
106 current Dog10K_Boxer_Tasha (GCF_000002285.5) 25 NC_006607.4 (51738743..51749088, complement)
106 current UU_Cfam_GSD_1.0 (GCF_011100685.1) 25 NC_049246.1 (51584115..51594478, complement)
106 current UMICH_Zoey_3.1 (GCF_005444595.1) 25 NC_049285.1 (51568255..51578566, complement)
106 current UNSW_CanFamBas_1.0 (GCF_013276365.1) 25 NC_049766.1 (51307418..51317739, complement)

Chromosome 25 - NC_051829.1Genomic Context describing neighboring genes Neighboring gene BCL2 family apoptosis regulator BOK Neighboring gene THAP domain containing 4 Neighboring gene autophagy related 4B cysteine peptidase Neighboring gene uncharacterized LOC119865877 Neighboring gene inhibitor of growth family member 5 Neighboring gene uncharacterized LOC111092467

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables UMP/dUMP kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables thymidylate kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in dTDP biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in dTTP biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in dUDP biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
thymidylate kinase
Names
one cut domain family member 3-like

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

  1. NC_051829.1 Reference ROS_Cfam_1.0

    Range
    51718398..51728728 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038436044.1 → XP_038291972.1  thymidylate kinase

    UniProtKB/TrEMBL
    A0A8C0LM58, A0A8C0TRN3
    Conserved Domains (1) summary
    cl17190
    Location:2 → 211
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

Alternate UMICH_Zoey_3.1

Genomic

  1. NC_049285.1 Alternate UMICH_Zoey_3.1

    Range
    51568255..51578566 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038510970.1 → XP_038366898.1  thymidylate kinase

    Conserved Domains (1) summary
    cl17190
    Location:2 → 211
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

Alternate UNSW_CanFamBas_1.0

Genomic

  1. NC_049766.1 Alternate UNSW_CanFamBas_1.0

    Range
    51307418..51317739 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038638697.1 → XP_038494625.1  thymidylate kinase

    Conserved Domains (1) summary
    cl17190
    Location:2 → 211
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

Alternate UU_Cfam_GSD_1.0

Genomic

  1. NC_049246.1 Alternate UU_Cfam_GSD_1.0

    Range
    51584115..51594478 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038574465.1 → XP_038430393.1  thymidylate kinase

    UniProtKB/TrEMBL
    A0A8C0LM58, A0A8C0TRN3
    Conserved Domains (1) summary
    cl17190
    Location:2 → 211
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

  1. NC_006607.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

    Range
    51738743..51749088 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038458682.1 → XP_038314610.1  thymidylate kinase

    UniProtKB/TrEMBL
    A0A8C0LM58, A0A8C0TRN3
    Conserved Domains (1) summary
    cl17190
    Location:2 → 211
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
Nucleotide Protein
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