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TJP2 tight junction protein 2 [ Dermochelys coriacea (leatherback sea turtle) ]

Gene ID: 119855955, updated on 8-May-2024

Summary

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Gene symbol
TJP2
Gene description
tight junction protein 2
See related
EnsemblRapid:ENSDCOG00030017165
Gene type
protein coding
RefSeq status
MODEL
Organism
Dermochelys coriacea
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira; Americhelydia; Chelonioidea; Dermochelyidae; Dermochelys
Orthologs
human mouse all
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Genomic context

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See TJP2 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
29
Annotation release Status Assembly Chr Location
101 current rDerCor1.pri.v4 (GCF_009764565.3) 5 NC_050072.1 (101054757..101148929, complement)
100 previous assembly rDerCor1.pri.v3 (GCF_009764565.2) 5 NC_050072.1 (101054757..101148966, complement)

Chromosome 5 - NC_050072.1Genomic Context describing neighboring genes Neighboring gene amyloid beta precursor protein binding family A member 1 Neighboring gene endosomal transmembrane epsin interactor 1 Neighboring gene uncharacterized LOC122460456 Neighboring gene phosphatidylinositol-4-phosphate 5-kinase type 1 beta Neighboring gene frataxin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cell adhesion molecule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell junction organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in establishment of endothelial intestinal barrier IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of blood-brain barrier permeability IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to cell-cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tight junction protein ZO-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Dermochelys coriacea Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference rDerCor1.pri.v4

Genomic

  1. NC_050072.1 Reference rDerCor1.pri.v4

    Range
    101054757..101148929 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038402935.1 → XP_038258863.1  tight junction protein ZO-2 isoform X4

    Related
    ENSDCOP00030048104.1, ENSDCOT00030051828.1
    Conserved Domains (5) summary
    cd12027
    Location:610 → 672
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:706 → 885
    GuKc; Guanylate kinase homologues
    smart00228
    Location:310 → 386
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:22 → 107
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01622
    Location:169 → 283
    SF-CC1; splicing factor, CC1-like family

  2. XM_043515432.1 → XP_043371367.1  tight junction protein ZO-2 isoform X8

    Conserved Domains (5) summary
    cd12027
    Location:597 → 659
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:693 → 872
    GuKc; Guanylate kinase homologues
    smart00228
    Location:297 → 373
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01622
    Location:156 → 270
    SF-CC1; splicing factor, CC1-like family

  3. XM_038402937.2 → XP_038258865.1  tight junction protein ZO-2 isoform X5

    Conserved Domains (5) summary
    cd12027
    Location:597 → 659
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:693 → 872
    GuKc; Guanylate kinase homologues
    smart00228
    Location:297 → 373
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01622
    Location:156 → 270
    SF-CC1; splicing factor, CC1-like family

  4. XM_038402938.2 → XP_038258866.1  tight junction protein ZO-2 isoform X5

    Conserved Domains (5) summary
    cd12027
    Location:597 → 659
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:693 → 872
    GuKc; Guanylate kinase homologues
    smart00228
    Location:297 → 373
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01622
    Location:156 → 270
    SF-CC1; splicing factor, CC1-like family

  5. XM_043515433.1 → XP_043371368.1  tight junction protein ZO-2 isoform X8

    Conserved Domains (5) summary
    cd12027
    Location:597 → 659
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:693 → 872
    GuKc; Guanylate kinase homologues
    smart00228
    Location:297 → 373
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01622
    Location:156 → 270
    SF-CC1; splicing factor, CC1-like family

  6. XM_038402946.2 → XP_038258874.1  tight junction protein ZO-2 isoform X5

    Related
    ENSDCOP00030048086.1, ENSDCOT00030051810.1
    Conserved Domains (5) summary
    cd12027
    Location:597 → 659
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:693 → 872
    GuKc; Guanylate kinase homologues
    smart00228
    Location:297 → 373
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01622
    Location:156 → 270
    SF-CC1; splicing factor, CC1-like family

  7. XM_038402941.2 → XP_038258869.1  tight junction protein ZO-2 isoform X5

    Related
    ENSDCOP00030047391.1, ENSDCOT00030050871.1
    Conserved Domains (5) summary
    cd12027
    Location:597 → 659
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:693 → 872
    GuKc; Guanylate kinase homologues
    smart00228
    Location:297 → 373
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01622
    Location:156 → 270
    SF-CC1; splicing factor, CC1-like family

  8. XM_043515430.1 → XP_043371365.1  tight junction protein ZO-2 isoform X8

    Conserved Domains (5) summary
    cd12027
    Location:597 → 659
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:693 → 872
    GuKc; Guanylate kinase homologues
    smart00228
    Location:297 → 373
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01622
    Location:156 → 270
    SF-CC1; splicing factor, CC1-like family

  9. XM_038402936.2 → XP_038258864.1  tight junction protein ZO-2 isoform X5

    Related
    ENSDCOP00030048099.1, ENSDCOT00030051823.1
    Conserved Domains (5) summary
    cd12027
    Location:597 → 659
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:693 → 872
    GuKc; Guanylate kinase homologues
    smart00228
    Location:297 → 373
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:9 → 94
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01622
    Location:156 → 270
    SF-CC1; splicing factor, CC1-like family

  10. XM_043515428.1 → XP_043371363.1  tight junction protein ZO-2 isoform X6

    Conserved Domains (5) summary
    cd12027
    Location:621 → 683
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:717 → 896
    GuKc; Guanylate kinase homologues
    smart00228
    Location:321 → 397
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:33 → 118
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01622
    Location:180 → 294
    SF-CC1; splicing factor, CC1-like family

  11. XM_038402934.2 → XP_038258862.2  tight junction protein ZO-2 isoform X1

    Related
    ENSDCOP00030048057.1, ENSDCOT00030051781.1
    Conserved Domains (5) summary
    cd12027
    Location:621 → 683
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:717 → 896
    GuKc; Guanylate kinase homologues
    smart00228
    Location:321 → 397
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:33 → 118
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01622
    Location:180 → 294
    SF-CC1; splicing factor, CC1-like family

  12. XM_038402943.2 → XP_038258871.2  tight junction protein ZO-2 isoform X2

    Related
    ENSDCOP00030048052.1, ENSDCOT00030051776.1
    Conserved Domains (5) summary
    cd12027
    Location:620 → 682
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:716 → 895
    GuKc; Guanylate kinase homologues
    smart00228
    Location:320 → 396
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:32 → 117
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01622
    Location:179 → 293
    SF-CC1; splicing factor, CC1-like family

  13. XM_043515429.1 → XP_043371364.1  tight junction protein ZO-2 isoform X7

    Conserved Domains (5) summary
    cd12027
    Location:620 → 682
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:716 → 895
    GuKc; Guanylate kinase homologues
    smart00228
    Location:320 → 396
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:32 → 117
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01622
    Location:179 → 293
    SF-CC1; splicing factor, CC1-like family

  14. XM_043515427.1 → XP_043371362.1  tight junction protein ZO-2 isoform X3

    Conserved Domains (5) summary
    cd12027
    Location:617 → 679
    SH3_ZO-2; Src homology 3 domain of the Tight junction protein, Zonula occludens protein 2
    smart00072
    Location:713 → 892
    GuKc; Guanylate kinase homologues
    smart00228
    Location:317 → 393
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:29 → 114
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    TIGR01622
    Location:176 → 290
    SF-CC1; splicing factor, CC1-like family
Nucleotide Protein
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