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TDP2 tyrosyl-DNA phosphodiesterase 2 [ Dermochelys coriacea (leatherback sea turtle) ]

Gene ID: 119851701, updated on 8-May-2024

Summary

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Gene symbol
TDP2
Gene description
tyrosyl-DNA phosphodiesterase 2
See related
EnsemblRapid:ENSDCOG00030014023
Gene type
protein coding
RefSeq status
MODEL
Organism
Dermochelys coriacea
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira; Americhelydia; Chelonioidea; Dermochelyidae; Dermochelys
Orthologs
human mouse all
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Genomic context

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See TDP2 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
8
Annotation release Status Assembly Chr Location
101 current rDerCor1.pri.v4 (GCF_009764565.3) 2 NC_050069.1 (107548424..107559257)
100 previous assembly rDerCor1.pri.v3 (GCF_009764565.2) 2 NC_050069.1 (107548481..107559258)

Chromosome 2 - NC_050069.1Genomic Context describing neighboring genes Neighboring gene chromosome 2 C6orf62 homolog Neighboring gene acyl-CoA thioesterase 13 Neighboring gene KIAA0319 ortholog Neighboring gene aldehyde dehydrogenase 5 family member A1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 5'-tyrosyl-DNA phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in double-strand break repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in PML body IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosyl-DNA phosphodiesterase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Dermochelys coriacea Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference rDerCor1.pri.v4

Genomic

  1. NC_050069.1 Reference rDerCor1.pri.v4

    Range
    107548424..107559257
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_043508294.1 → XP_043364229.1  tyrosyl-DNA phosphodiesterase 2 isoform X2

    Conserved Domains (2) summary
    cd09080
    Location:150 → 394
    TDP2; Phosphodiesterase domain of human TDP2, a 5'-tyrosyl DNA phosphodiesterase, and related domains
    cd14344
    Location:65 → 101
    UBA_TYDP2; UBA-like domain found in tyrosyl-DNA phosphodiesterase 2 (TDP2) and similar proteins

  2. XM_043508293.1 → XP_043364228.1  tyrosyl-DNA phosphodiesterase 2 isoform X1

    Related
    ENSDCOP00030039142.1, ENSDCOT00030041612.1
    Conserved Domains (2) summary
    cd09080
    Location:152 → 396
    TDP2; Phosphodiesterase domain of human TDP2, a 5'-tyrosyl DNA phosphodiesterase, and related domains
    cd14344
    Location:67 → 103
    UBA_TYDP2; UBA-like domain found in tyrosyl-DNA phosphodiesterase 2 (TDP2) and similar proteins

  3. XM_043508295.1 → XP_043364230.1  tyrosyl-DNA phosphodiesterase 2 isoform X3

    Conserved Domains (2) summary
    cd09080
    Location:131 → 375
    TDP2; Phosphodiesterase domain of human TDP2, a 5'-tyrosyl DNA phosphodiesterase, and related domains
    cd14344
    Location:46 → 82
    UBA_TYDP2; UBA-like domain found in tyrosyl-DNA phosphodiesterase 2 (TDP2) and similar proteins

  4. XM_043508296.1 → XP_043364231.1  tyrosyl-DNA phosphodiesterase 2 isoform X4

    Conserved Domains (2) summary
    cd09080
    Location:121 → 365
    TDP2; Phosphodiesterase domain of human TDP2, a 5'-tyrosyl DNA phosphodiesterase, and related domains
    cd14344
    Location:36 → 72
    UBA_TYDP2; UBA-like domain found in tyrosyl-DNA phosphodiesterase 2 (TDP2) and similar proteins
Nucleotide Protein
Heading Accession and Version

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