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FLT3 fms related receptor tyrosine kinase 3 [ Dermochelys coriacea (leatherback sea turtle) ]

Gene ID: 119850618, updated on 8-May-2024

Summary

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Gene symbol
FLT3
Gene description
fms related receptor tyrosine kinase 3
See related
EnsemblRapid:ENSDCOG00030017985
Gene type
protein coding
RefSeq status
MODEL
Organism
Dermochelys coriacea
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira; Americhelydia; Chelonioidea; Dermochelyidae; Dermochelys
Orthologs
human mouse all
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Genomic context

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See FLT3 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
31
Annotation release Status Assembly Chr Location
101 current rDerCor1.pri.v4 (GCF_009764565.3) 1 NC_050068.2 (45233856..45323541, complement)
100 previous assembly rDerCor1.pri.v3 (GCF_009764565.2) 1 NC_050068.1 (45233784..45324177, complement)

Chromosome 1 - NC_050068.2Genomic Context describing neighboring genes Neighboring gene pancreatic and duodenal homeobox 1 Neighboring gene caudal type homeobox 2 Neighboring gene uncharacterized LOC122457912 Neighboring gene poly(A) specific ribonuclease subunit PAN3 Neighboring gene uncharacterized LOC122457913

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in B cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
receptor-type tyrosine-protein kinase FLT3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Dermochelys coriacea Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference rDerCor1.pri.v4

Genomic

  1. NC_050068.2 Reference rDerCor1.pri.v4

    Range
    45233856..45323541 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_043504341.1 → XP_043360276.1  receptor-type tyrosine-protein kinase FLT3 isoform X2

    Conserved Domains (1) summary
    cl21453
    Location:563 → 941
    PKc_like; Protein Kinases, catalytic domain

  2. XM_043504342.1 → XP_043360277.1  receptor-type tyrosine-protein kinase FLT3 isoform X2

    Conserved Domains (1) summary
    cl21453
    Location:563 → 941
    PKc_like; Protein Kinases, catalytic domain

  3. XM_043504347.1 → XP_043360282.1  receptor-type tyrosine-protein kinase FLT3 isoform X3

    Related
    ENSDCOP00030049211.1, ENSDCOT00030053379.1
    Conserved Domains (1) summary
    cl21453
    Location:540 → 918
    PKc_like; Protein Kinases, catalytic domain

  4. XM_043504350.1 → XP_043360285.1  receptor-type tyrosine-protein kinase FLT3 isoform X5

    Conserved Domains (1) summary
    cl21453
    Location:527 → 905
    PKc_like; Protein Kinases, catalytic domain

  5. XM_043504349.1 → XP_043360284.1  receptor-type tyrosine-protein kinase FLT3 isoform X5

    Conserved Domains (1) summary
    cl21453
    Location:527 → 905
    PKc_like; Protein Kinases, catalytic domain

  6. XM_043504348.1 → XP_043360283.1  receptor-type tyrosine-protein kinase FLT3 isoform X4

    Related
    ENSDCOP00030049185.1, ENSDCOT00030053353.1
    Conserved Domains (1) summary
    cl21453
    Location:528 → 906
    PKc_like; Protein Kinases, catalytic domain

  7. XM_043504346.1 → XP_043360281.1  receptor-type tyrosine-protein kinase FLT3 isoform X3

    Conserved Domains (1) summary
    cl21453
    Location:540 → 918
    PKc_like; Protein Kinases, catalytic domain

  8. XM_043504340.1 → XP_043360275.1  receptor-type tyrosine-protein kinase FLT3 isoform X1

    Conserved Domains (1) summary
    cl21453
    Location:587 → 965
    PKc_like; Protein Kinases, catalytic domain

  9. XM_043504343.1 → XP_043360278.1  receptor-type tyrosine-protein kinase FLT3 isoform X2

    Conserved Domains (1) summary
    cl21453
    Location:563 → 941
    PKc_like; Protein Kinases, catalytic domain

  10. XM_043504344.1 → XP_043360279.1  receptor-type tyrosine-protein kinase FLT3 isoform X2

    Related
    ENSDCOP00030049133.1, ENSDCOT00030053286.1
    Conserved Domains (1) summary
    cl21453
    Location:563 → 941
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version

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