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Capn3 calpain 3 [ Arvicola amphibius (Eurasian water vole) ]

Gene ID: 119814387, updated on 21-Mar-2024

Summary

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Gene symbol
Capn3
Gene description
calpain 3
See related
EnsemblRapid:ENSAAPG00005008147
Gene type
protein coding
RefSeq status
MODEL
Organism
Arvicola amphibius
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Arvicolinae; Arvicola
Orthologs
human mouse all
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Genomic context

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See Capn3 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
24
Annotation release Status Assembly Chr Location
101 current mArvAmp1.2 (GCF_903992535.2) 5 NC_052051.1 (55152623..55204612, complement)
100 previous assembly mArvAmp1.1 (GCF_903992535.1) 5 NC_052051.1 (55152623..55204612, complement)

Chromosome 5 - NC_052051.1Genomic Context describing neighboring genes Neighboring gene synaptosome associated protein 23 Neighboring gene zinc finger protein 106 Neighboring gene glucosidase alpha, neutral C Neighboring gene transmembrane protein 87A Neighboring gene VPS39 subunit of HOPS complex

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium-dependent cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
calpain-3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Arvicola amphibius Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mArvAmp1.2

Genomic

  1. NC_052051.1 Reference mArvAmp1.2

    Range
    55152623..55204612 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038330034.1 → XP_038185962.1  calpain-3 isoform X2

    Conserved Domains (3) summary
    cd16190
    Location:568 → 736
    EFh_PEF_CAPN3; Calcium-activated neutral
    pfam00648
    Location:84 → 374
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:395 → 533
    Calpain_III; Calpain large subunit, domain III

  2. XM_038330033.1 → XP_038185961.1  calpain-3 isoform X1

    Conserved Domains (3) summary
    cd16190
    Location:568 → 764
    EFh_PEF_CAPN3; Calcium-activated neutral
    pfam00648
    Location:84 → 374
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:395 → 533
    Calpain_III; Calpain large subunit, domain III

  3. XM_038330036.1 → XP_038185964.1  calpain-3 isoform X4

    Related
    ENSAAPP00005010845.1, ENSAAPT00005011895.2
    Conserved Domains (4) summary
    cd16190
    Location:612 → 780
    EFh_PEF_CAPN3; Calcium-activated neutral
    pfam00648
    Location:84 → 374
    Peptidase_C2; Calpain family cysteine protease
    pfam01067
    Location:395 → 533
    Calpain_III; Calpain large subunit, domain III
    pfam16648
    Location:542 → 612
    Calpain_u2; Unstructured region on Calpain-3

  4. XM_042055072.1 → XP_041911006.1  calpain-3 isoform X3

    Conserved Domains (2) summary
    cd00214
    Location:33 → 164
    Calpain_III; Calpain, subdomain III. Calpains are calcium-activated cytoplasmic cysteine proteinases, participate in cytoskeletal remodeling processes, cell differentiation, apoptosis and signal transduction. Catalytic domain and the two calmodulin-like domains are ...
    cd16190
    Location:190 → 358
    EFh_PEF_CAPN3; Calcium-activated neutral
Nucleotide Protein
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