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CHRNA3 cholinergic receptor nicotinic alpha 3 subunit [ Choloepus didactylus (southern two-toed sloth) ]

Gene ID: 119531724, updated on 21-Mar-2024

Summary

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Gene symbol
CHRNA3
Gene description
cholinergic receptor nicotinic alpha 3 subunit
See related
EnsemblRapid:ENSCDIG00005025214
Gene type
protein coding
RefSeq status
MODEL
Organism
Choloepus didactylus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Xenarthra; Pilosa; Folivora; Megalonychidae; Choloepus
Orthologs
human mouse all
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Genomic context

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See CHRNA3 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
9
Annotation release Status Assembly Chr Location
100 current mChoDid1.pri (GCF_015220235.1) 4 NC_051310.1 (100322283..100342036, complement)

Chromosome 4 - NC_051310.1Genomic Context describing neighboring genes Neighboring gene proteasome 20S subunit alpha 4 Neighboring gene putative homeodomain transcription factor 1 Neighboring gene U6 spliceosomal RNA Neighboring gene cholinergic receptor nicotinic alpha 5 subunit Neighboring gene iron-sulfur cluster assembly 1 homolog, mitochondrial-like Neighboring gene cholinergic receptor nicotinic beta 4 subunit Neighboring gene 60 kDa heat shock protein, mitochondrial-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_051310.1 Chromosome 4 Reference mChoDid1.pri Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 2 iron, 2 sulfur cluster binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables acetylcholine-gated monoatomic cation-selective channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nervous system process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of membrane potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
neuronal acetylcholine receptor subunit alpha-3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Choloepus didactylus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mChoDid1.pri Primary Assembly

Genomic

  1. NC_051310.1 Reference mChoDid1.pri Primary Assembly

    Range
    100322283..100342036 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_037833296.1 → XP_037689224.1  neuronal acetylcholine receptor subunit alpha-3 isoform X1

    Related
    ENSCDIP00005036005.1, ENSCDIT00005040478.1
    Conserved Domains (2) summary
    TIGR00860
    Location:34 → 500
    LIC; Cation transporter family protein
    cd19016
    Location:39 → 245
    LGIC_ECD_nAChR_A3; extracellular domain of nicotinic acetylcholine receptor subunit alpha 3 (CHRNA3)

  2. XM_037833300.1 → XP_037689228.1  neuronal acetylcholine receptor subunit alpha-3 isoform X3

    Conserved Domains (3) summary
    cd03558
    Location:92 → 106
    LGIC_ECD; Cys-loop [structural motif]
    cl28912
    Location:1 → 174
    LGIC_ECD; extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))
    pfam02932
    Location:181 → 428
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

  3. XM_037833299.1 → XP_037689227.1  neuronal acetylcholine receptor subunit alpha-3 isoform X3

    Conserved Domains (3) summary
    cd03558
    Location:92 → 106
    LGIC_ECD; Cys-loop [structural motif]
    cl28912
    Location:1 → 174
    LGIC_ECD; extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))
    pfam02932
    Location:181 → 428
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

  4. XM_037833297.1 → XP_037689225.1  neuronal acetylcholine receptor subunit alpha-3 isoform X2

    Conserved Domains (2) summary
    TIGR00860
    Location:3 → 469
    LIC; Cation transporter family protein
    cd19016
    Location:8 → 214
    LGIC_ECD_nAChR_A3; extracellular domain of nicotinic acetylcholine receptor subunit alpha 3 (CHRNA3)

  5. XM_037833298.1 → XP_037689226.1  neuronal acetylcholine receptor subunit alpha-3 isoform X2

    Related
    ENSCDIP00005036055.1, ENSCDIT00005040534.1
    Conserved Domains (2) summary
    TIGR00860
    Location:3 → 469
    LIC; Cation transporter family protein
    cd19016
    Location:8 → 214
    LGIC_ECD_nAChR_A3; extracellular domain of nicotinic acetylcholine receptor subunit alpha 3 (CHRNA3)

  6. XM_037833301.1 → XP_037689229.1  neuronal acetylcholine receptor subunit alpha-3 isoform X3

    Conserved Domains (3) summary
    cd03558
    Location:92 → 106
    LGIC_ECD; Cys-loop [structural motif]
    cl28912
    Location:1 → 174
    LGIC_ECD; extracellular domain (ECD) of Cys-loop neurotransmitter-gated ion channels (also known as ligand-gated ion channel (LGIC))
    pfam02932
    Location:181 → 428
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region
Nucleotide Protein
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