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PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 [ Talpa occidentalis (Iberian mole) ]

Gene ID: 119259604, updated on 21-Mar-2024

Summary

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Gene symbol
PFKFB4
Gene description
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
Gene type
protein coding
RefSeq status
MODEL
Organism
Talpa occidentalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Eulipotyphla; Talpidae; Talpa
Orthologs
human mouse all
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Genomic context

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See PFKFB4 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
19
Annotation release Status Assembly Chr Location
RS_2023_03 current MPIMG_talOcc4v2.1 (GCF_014898055.3) Unplaced Scaffold NW_023600993.1 (34013039..34047309, complement)

NW_023600993.1Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 51 Neighboring gene ATR interacting protein Neighboring gene shisa family member 5 Neighboring gene three prime repair exonuclease 1 Neighboring gene collagen type VII alpha 1 chain Neighboring gene urocortin 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_023600993 Unplaced Scaffold Reference MPIMG_talOcc4v2.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 6-phosphofructo-2-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fructose-2,6-bisphosphate 2-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fructose 2,6-bisphosphate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in fructose metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_014898055.3-RS_2023_03

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference MPIMG_talOcc4v2.1 Primary Assembly

Genomic

  1. NW_023600993.1 Reference MPIMG_talOcc4v2.1 Primary Assembly

    Range
    34013039..34047309 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_037528601.2 → XP_037384498.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform X3

    Conserved Domains (2) summary
    pfam00300
    Location:241 → 427
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:24 → 238
    6PF2K; 6-phosphofructo-2-kinase

  2. XM_037528599.2 → XP_037384496.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform X2

    Conserved Domains (2) summary
    pfam00300
    Location:251 → 437
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:34 → 248
    6PF2K; 6-phosphofructo-2-kinase

  3. XM_037528594.2 → XP_037384491.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform X1

    Conserved Domains (2) summary
    pfam00300
    Location:252 → 438
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:35 → 249
    6PF2K; 6-phosphofructo-2-kinase

  4. XM_037528606.2 → XP_037384503.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform X5

    Conserved Domains (2) summary
    pfam00300
    Location:218 → 404
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:1 → 215
    6PF2K; 6-phosphofructo-2-kinase

  5. XM_037528613.2 → XP_037384510.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform X5

    Conserved Domains (2) summary
    pfam00300
    Location:218 → 404
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:1 → 215
    6PF2K; 6-phosphofructo-2-kinase

  6. XM_037528603.2 → XP_037384500.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform X5

    Conserved Domains (2) summary
    pfam00300
    Location:218 → 404
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:1 → 215
    6PF2K; 6-phosphofructo-2-kinase

  7. XM_054693906.1 → XP_054549881.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform X5

  8. XM_037528602.2 → XP_037384499.1  6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 isoform X4

    Conserved Domains (2) summary
    pfam00300
    Location:252 → 414
    His_Phos_1; Histidine phosphatase superfamily (branch 1)
    pfam01591
    Location:35 → 249
    6PF2K; 6-phosphofructo-2-kinase
Nucleotide Protein
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