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Cbl E3 ubiquitin-protein ligase CBL [ Bradysia coprophila ]

Gene ID: 119080678, updated on 24-May-2024

Summary

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Gene symbol
Cbl
Gene description
E3 ubiquitin-protein ligase CBL
Gene type
protein coding
RefSeq status
MODEL
Organism
Bradysia coprophila
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Sciaroidea; Sciaridae; Bradysia
Orthologs
fruit fly all
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Genomic context

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Location:
chromosome: Un
Exon count:
8
Annotation release Status Assembly Chr Location
100 current BU_Bcop_v1 (GCF_014529535.1) Unplaced Scaffold NW_023503608.1 (9418796..9432993)

NW_023503608.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC119080738 Neighboring gene acetylcholinesterase Neighboring gene FK506-binding protein 2-like Neighboring gene beta-galactosidase-1-like protein 2 Neighboring gene beta-galactosidase-1-like protein 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_023503608 Unplaced Scaffold Reference BU_Bcop_v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables SH3 domain binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphotyrosine residue binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables receptor tyrosine kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of epidermal growth factor-activated receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane raft IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase CBL; E3 ubiquitin-protein ligase CBL-B-B

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bradysia coprophila Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference BU_Bcop_v1

Genomic

  1. NW_023503608.1 Reference BU_Bcop_v1

    Range
    9418796..9432993
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_037189111.1 → XP_037045006.1  E3 ubiquitin-protein ligase CBL-B-B isoform X1

    Conserved Domains (5) summary
    cd09920
    Location:240 → 334
    SH2_Cbl-b_TKB; Src homology 2 (SH2) domain found in the Cbl-b TKB domain
    cd14318
    Location:836 → 875
    UBA_Cbl_like; UBA domain found in casitas B-lineage lymphoma (Cbl) proteins
    cd16709
    Location:347 → 412
    RING-HC_Cbl-b; RING finger, HC subclass, found in E3 ubiquitin-protein ligase Cbl-b and similar proteins
    pfam02262
    Location:38 → 156
    Cbl_N; CBL proto-oncogene N-terminal domain 1
    pfam02761
    Location:163 → 246
    Cbl_N2; CBL proto-oncogene N-terminus, EF hand-like domain

  2. XM_037189112.1 → XP_037045007.1  E3 ubiquitin-protein ligase CBL isoform X2

    Conserved Domains (4) summary
    cd09920
    Location:240 → 334
    SH2_Cbl-b_TKB; Src homology 2 (SH2) domain found in the Cbl-b TKB domain
    cd16709
    Location:347 → 412
    RING-HC_Cbl-b; RING finger, HC subclass, found in E3 ubiquitin-protein ligase Cbl-b and similar proteins
    pfam02262
    Location:38 → 156
    Cbl_N; CBL proto-oncogene N-terminal domain 1
    pfam02761
    Location:163 → 246
    Cbl_N2; CBL proto-oncogene N-terminus, EF hand-like domain
Nucleotide Protein Strain
Heading Accession and Version

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